1. Introduction
Absence Seizures have been a medical concern for a long time, and were first described in medical literature back in 1705 by Poupart (Temkin, 1971). According to The World Health Organization (WHO) at least 40 forms of epilepsy have been identified, and they are characterized by an abrupt and transitory synchronization of neuron activities, whose causes are not always well known.
2. Overview and Clinical Presentation of Absence Seizures
2.1 Overview
According to the American Epilepsy Society, (2014), Absence Seizures (AS), which in the past were called ‘petit mal’, are a type of generalized seizure. In 1935, Gibbs, Davis, and Lennox described a typical pattern of AS, consisting of a correlation between the episodes of diminished consciousness and 3-4 Hz spike-wave discharges (SWD) on electroencephalograms (EEGs), which is a valid association to date (Blumenfield,
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Moreover, typical absences usually last 9–12 s (Hooge, & De Deyn, 2001). Indeed, mutations of genes coding for GABA A receptors and T-type calcium channels have been linked to AS. More recent studies have found that Glucose transporters might also be linked to AS, however data is limited in this respect and offers further room for exploration.
The pathophysiological theories hypothesized to date, have clearly always recognised the contribution of two forebrain structures, the thalamus and the cerebral cortex, and their fundamental roles in the generation of seizures. However, many recent findings state that even when focusing on a particular network (e.g. the thalamus), different cellular (e.g. channels) as well as molecular dysfunctions can occur, which may lead to irregular brain rhythms and associated cognitive difficulties (Avoli,
So, Lia was getting the wrong dosage of medications or not even getting medications. The doctors wanted to check her blood to know whether the medications were actually helping her or not. But they have realized that Lia’s mother has been lying or confused about how she administered the medications to her throughout this time (Guerrero et al, 2002). The next time Lia had a grand mal seizure; her parents blamed it on all the medications that were prescribed to
The “Spirit Catches You and You Fall Down” by Anne Fadiman is the story of a refugee family from Laos in the United States. The story develops over the tragic case of one of the family’s daughters named Lia, who suffers from epilepsy. The book describes the Hmong’ beliefs and medical Western practices in medicine and how it influences Lia’s life. In addition, the book relates the barriers of becoming part of a new culture, the Western perspective in medicine, and the misunderstanding between the doctors and the Hmong due to the collision of the cultures and the differences of knowledge.
1. How did you notice culture impacting the health and illness course of Lia Lee and her family in these beginning chapters? Culture plays a big role in the in the course of illness of Lia Lee. In chapter one of the book, it already gave the reader a glimpse of how different Hmong and American culture are when it comes to giving birth and naming a child.
There are more plausible solutions such as a lack of medical knowledge, convulsive
When James was younger, he suffered from psychosomatic, or stress-induced seizures, similar to epileptic
Social influences were also a big factor in my episode of seizing. My best friend went to find help, the teachers helped carry me into a different room, and everyone that was near stopped what they were doing to crowd over me. Once I was in the different room an upperclassman, which had been diagnosed with epilepsy, explained that after she seizes she would always throw up too. She told me that it was all going to be fine, and that really helped me. Developmental influences also have occurred.
Transcranial magnetic stimulation (TMS) is a non-invasive tool for the electrical stimulation of neural tissue, including cerebral cortex, spinal roots, and cranial and peripheral nerves. TMS can be applied as single pulses of stimulation, pairs of stimuli separated by variable intervals to the same or different brain areas, or as trains of repetitive stimuli at various frequencies. Single stimuli can depolarise neurons and evoke measurable effects. Trains of stimuli (repetitive TMS) can modify excitability of the cerebral cortex at the stimulated site and also at remote areas along functional anatomical connections. Transcranial magnetic stimulation might provide novel insights into the pathophysiology of the neural circuitry underlying neurological and psychiatric disorders, be developed into
Here, Churchland will say that only “hardware” matters and that if there’s enough neuroscience, we can see what you are thinking and picturing in your brain. She says that all fields interact/ come together to understand the brain. There’s no conflict, they all work together to a certain angle (Churchland, pg.
Absence seizures are seizures characterized by brief lapses of consciousness, usually lasting no more than ten seconds. Eye-blinking and twitching of the mouth may accompany these seizures. During this seizure, the brain ceases to function as it normally would. A person’s consciousness is altered in an almost imperceptible manner. This seizure could happen almost 100 times a day.
Define thymatron: The Thymatron® System IV provides several computer-automated, end-of-treatment reports of seizure amplitude (Maximum Sustained Power, Seizure Energy Index), symmetry (Maximum Sustained Coherence), and termination (Postictal Suppression Index), providing immediate feedback on several key aspects of seizure quality.1 The Thymatron®instrument is the first modern device to provide an Ultrabrief stimulus. It remains the only one that can deliver the same stimulus across the entire dosage range The unequaled safety record of the Thymatron® instrument comes from its multiple redundant levels of error protection and operating efficiency.
The catatonic type [Greek. / Latin. Catatonia: voltage madness] This type occurs less frequently today than in the past. Seclusion and immobility are the main symptoms; the patient moves and behaves like a ‘statue’. He cannot move, not because he is paralyzed, but because his ability to command his limps is disrupted.
Epilepsy can also occur when there is a genetic mutation in the nerve cells, also known as neurons, located in the brain. Epilepsy can also be developed. Some ways you can develop Epilepsy is if you have had trauma to the head (such as brain tumor or stroke), a disease infecting the brain (such as meningitis), or prenatal brain damage (when the babies are in the womb, they are sensitive to brain damage that can be caused by poor nutrition or lack of oxygen). Slide 9 (Is There a Way to Prevent Epilepsy?):
Prognosis for febrile seizures, whether it’s simple or complex, are generally favorable and the child will eventually outgrow this condition. Forty percent of children who experience convulsions, however, would likely have another one within two years, according to
Cysticercosis is a common parasitic infection caused by the larvae of the tapeworm Taenia solium. An individual may contract the infection by ingesting the tapeworm eggs, which can then hatch, and the larvae migrate to various tissues of your body including your brain. When the larvae form cysts in the central nervous system, the infection is then referred to as neurocysticercosis (1). Having these parasites in your brain can cause many neurological issues such as intracranial hypertension and epilepsy. In fact, neurocysticercosis is one of the major causes of adult-onset epilepsy (2).
The main mechanism is, as hippocampus is intensity sensitive to stress and the stress hormone glucocorticoids (GCs) (Bruce et al