Synthetic Heterocycles
1.Introduction: Ox diazole, a heterocycles nucleus has attracted a wide attention of the chemist in search for new therapeutic molecules.Five member heterocycles compounds show various type of biological activities among than 2,5-distributed 1,3,4-ox diazole are associated with diverse biological activities [2]. Various biological activities like antimicrobial, anti-tubercular, anti-inflammatory, Anticonvulsant [3], Hypnotic , Anesthetic activity [4]. 1,3,4-ox diazole showed antibacterial properties similar to those of well known sulfonamide drugs. The ox diazole nucleus with N=C-S linkage exhibits a large number of pharmacological activities [5]. Sulfone derivatives containing heterocycles moiety are known for their interesting …show more content…
The chemistry of heterocycles compounds is one of the most complex branches of chemistry. It is equally interesting for its theoretical implication for the diversity of its synthetic procedure and for the physiological and industrial significance. Synthetic heterocycles chemistry has influenced almost every place of human life and the heterocycles compounds have found their application in diverse fields medicine, agriculture, polymer, and various industries. Synthetic heterocycles drugs are used as Hypnotics, Anticonvulsants, Antiseptics, Antineoplastics, Antiviral, Antihistaminic, Anti-tumor etc. Majority of the large number of drugs being introduces in pharmacopeias every year are heterocycles …show more content…
The chemistry of heterocycles compounds is one of the most complexes of branches of chemistry. It is equally interesting for its theoretical implication for the diversity of its synthetic procedure and for the physiological and industrial significance. Synthetic heterocycles chemistry has influenced almost every place of human life and the heterocycles compounds have found their application in diverse field as medicine, agriculture, polymer, and various industries. The proposed work is in context with the compounds having 1,3,4-ox diazoles moiety. The other moieties like azetidinones, pyrrole and pyrolidines etc. also present and these moieties containing drugs have potential utility. Thus the combined molecules of 1,3,4-oxadiazoles and these heterocycles, it is expected that the novel heterocycles will have good antimicrobial properties and will be applied as
Triphenylethanol Synthesis Lab Report
1804 Words | 8 PagesMany sources of error were responsible for recovering a small amount of product. Introduction: The carbon-carbon bond formation is an important tool in organic chemistry to construct the simple as well as an organic compound. There are several
Unknown Compounds
1643 Words | 7 PagesPhysically, the unknown compound was composed of white, grainy, crystal-like structures. The unknown was also odorless. From these observations, various physical and chemical testing was performed to determine properties of the unidentified compound. A series of solubility tests were performed, as shown in Table 2, and revealed that the unknown compound was soluble in water, but not in Acetone or Toluene.
Unknown Compounds
469 Words | 2 PagesIn this lab, three unknown compounds were separated from a mixture and identified by melting point. Unknown mixture #124 has components of acid, base and neutral compound. The compounds were identified by melting point and matched up with the known melting points from a given list. In order to identify the compound it was important to separate by dissolving the mixture in an organic solvent which was not soluble in water, and then extracting the solution first with HCl, and then dilute sodium hydroxide solution. From the separation mixture, the aqueous layer were obtained and labeled as TT-1 (base), TT-2(acid) and TT-3 (neutral) in three different test tubes for later recovery.
Opioid Use Of Morphine: A Case Study
558 Words | 3 PagesMorphine and methadone are life-long treatment which means it must be taken throughout life and cause dependence property to existing (Bell & Zador, 2000). Furthermore, if the treatment has stop or reduced slowly because consumer has started too relieved from pain, morphine withdrawal symptoms may relapse because body try to maintain balance state. This behavior is one of concern by society today where drug abuse behavioral giving bad impact to the society and government (Black, 2016). Given the limitations of morphine and methadone as pain medication and management, alternative potential compound of natural product is suggested. Alternative potential compound has widely used in pharmaceutical industry.
Over Three Decade Of Synthetic Organic Chemistry Summary
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Dexmedetomidine
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Unknown Compounds
1027 Words | 5 PagesFirst, two grams on an unknown white compound were given. The possible compounds the known could be were CaCO3, KNO3, NH4Cl, CaCl2, K2SO4, (NH4)2SO2, Ca(NO3)2, NaC2H2O2, K2CO3, MgCl2, Na2CO3, 0.1 M AgNO3, MgSO4, NaCl, 0.2 M BaCl2, KCl, NaSO4, Mg(s), HCl, HNO3, NaOH, HC2H3O2, H2SO4, and KOH. The solubility test required using a scale to measure .575 of our unknown white compound. The unknown compound was measured in a 100 mL beaker.
Synthesis Of 3-Nitrochalcone Lab Report
391 Words | 2 PagesNext, the oxygen is protonated from the 3-nitrobenzaldehyde, which is then followed by an elimination reaction where this acts as a leaving group. The product is the trans-alkene present in the product. After the reaction was completed, purification of the product was conducted using semi-microscale recrystallization.
N-Dimethyl Formamide
713 Words | 3 Pages2.1 Material N,N-Dimethyl formamide (DMF), 2,2-Azobisisobutyronitrile (AIBN), Silver nitrate (AgNO3) and Methanol were purchased from the lobachemie Pvt. Ltd. (India). Styrene monomer was procured from the sigma-Aldrich. Co. The solvents DMF and methanol were distilled for purification.
Pros And Cons Of Synthetic Medicine
1704 Words | 7 PagesSynthetic drugs are created in laboratories and causes unacceptable side effects. Herbal drugs are thought to be effective because people have been using them for thousands of years and are reporting
Organic Chemistry Case Study
1496 Words | 6 Pages1.Chemical properties Elemental mercury (Hg) has an atomic weight of 200.59 u, oxidation states 0, +1 and +2. Is a liquid and volatile metal soluble in water to some extents? In the oxidation states +1 and +2 is able to form organic compounds of type RHgX and R2Hg where R can be alkyl- or Aryl groups. The RHgX compounds properties depend on the nature of the X rest; If the organic compound contents hologenides the result is a highly lipophilic compound whereas If the rest is oxygen anion, chemically stable, thermally labile and light sensitive compounds are formed. Nevertheless, away from the properties differences, both kind of compounds are crystalline.
Toluene Solubility
197 Words | 1 PagesSolubility of the compound was determined in different solvents like hydrochloric acid, sul-furic acid, sodium hydroxide, methanol, ethanol, acetone, ethyl acetate, chloroform, DMSO, glacial acetic acid, n-hexane, cyclohexane, n-octanol, diethyl ether, benzene, toluene and wa-ter, followed by the preparation of saturated solution with those solvents which shows good solubility with the synthesized compound and then plotted a linear calibration curve to de-termine the concentration. The solubility determination was based on the USP Criteria (Low Y and Law SL., 1996; Lalitha Y and Lakshmi PK., 2011). 2.7.3. pH 10 mg of the synthesized compound was weighed accurately and placed into three separate volumetric flasks containing suitable solvents
Hydroquinone Study
1068 Words | 5 PagesThis was due to an interesting effect of the methoxy identity of 1, 4-benzoquinones. The MIC determination of methoxybenzoquinone (MBQ) against S. typhimurium was found to be significantly lower than that of DMBQ (512 and 32 μg/mL, respectively). The difference in the number of methoxy groups in the 1, 4-benzoquinones significantly affected their antibacterial activities against the Gram-negative bacteria S. typhimurium and E. coli. Furthermore, hydroquinone (HQ), a reduced form of BQ, had significantly lower antibacterial activity than
Saffranal
2042 Words | 9 PagesSaffranal is the aglycon of picocrocin and are responsible for many pharmacological actions (26-27). Saffron is having approximately 40–50 different constituents including various carbohydrates, minerals, mucilage, vitamins, pigments, Flavenoids, amino acids, proteins, starch and gums (28). But crocin and saffranal were found pharmaceutically more useful than other. Pharmacological studies have demonstrated radical scavenging (29), antiepileptic, neuroprotective, anti-diabetic, antioxidant (30), anti- inflammatory and antinociceptive properties for crocin and saffranal. Pharmacological studies have demonstrated antiepileptic, neuroprotective, anti-diabetic, antioxidant, anti-inflammatory¸ and antinociceptive properties for crocin and saffranal
Gingivitis Research Paper
1207 Words | 5 PagesIntroduction Gingivitis is the inflammation of the gingiva. Plaque is a requirement for the development of gingivitis (Informational Paper, 1999). Periodontitis is a polymicrobial disease in which disease expression involves intricate interactions of the plaque biofilm with the host inflammatory response and subsequent alterations in bone and connective tissue metabolism (Kornman, 2008)1. Although mechanical plaque control methods have the potential to maintain adequate levels of oral hygiene, clinical experience and population-based studies have shown that such methods are not being employed as accurately as they should be by a large number of people. Therefore, several chemotherapeutic agents have been developed to control bacterial plaque,
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