The previous literature review went over some of the latest ideology and approaches in cognitive behavioral therapy and psychopharmacology. This literature review will explore the methods and techniques used to carry out these current approaches in case-studies or clinical trials. One case-studies examines cognitive-behavioral and interpersonal psychotherapy in the treatment for depression in Puerto Rican adolescents. Another study is a case study of Vilazodone in the treatment of major depression, measuring efficiency and severity of depression. Research models will be closely looked at to identify how research methods can be carried out. The first case study “The efficacy of cognitive-behavioral and interpersonal treatments for depression …show more content…
Sessions 1-4 focused on how thoughts influence mood, sessions 5-8 focused on how daily activities influence mood, and sessions 9-12 focused on how interactions with other people affect mood. The rationale and goals of CBT were discussed with the adolescents. Also ground rules about scheduling and confidentiality were reviewed as well. The definition of depression is discussed, and therapist relate it to the adolescent's feelings and experiences. Adolescents are asked to complete a Daily Mood Scale everyday for the first week of therapy. The next three weeks of the first theme focus on cognition and the “A-B-C-D cognitive technique” is introduced. This technique allows participants to apply their experiences to a thought correcting method that identifies activating events, beliefs about the events, consequences, and allows an opportunity to dispute thoughts. In sessions, 5-8, daily mood graphs and the pleasant activities list are introduced and used by participants until session 12. Adolescent are taught that creating a plan to overcome depression that requires setting reasonable goals and focusing on positive actions to reach those …show more content…
The severity of the depression is categorized by a score on a scale that measures depression such as the Hamilton Depression Rating Scale (HAMD) or the Montgomery- Asberg Depression Rating scale (MADRS). For example a score greater than 25-28 on the HAMD or greater that 28-30 on the MADRS is an indication of severe depression. Both studies were required to be double-blind, randomized, and placebo-controlled. Patients were randomized to receive either vilazodone or placebo for 8 weeks of double-blind treatment. The dosage of Vilazodone was increased steadily to a target 40-mg dose. Patients were given one dose daily. There was a fixed-dose schedule of 10 mg for the first 7 days, 20 mg for the following 7 days, and 40 mg for the remainder of the studies. Efficacy was assessed at week 0 (the baseline) and at weeks 1, 2, 4, 6, and