Introduction: Energy is the ability to promote change or to do work. This kind of ability is very critical for living organisms. Therefore, they gain energy from different resources to obtain body maintenance and different body functions. The human body cells carry out number of reactions to get energy from the breaking down of nutrients such as carbohydrates, proteins, and fats. Consequently, producing energy that is needed for metabolic pathways, including the synthesis of different components or the breakdown of others. Cells enroll in a process called cellular respiration in the presence of Oxygen for the making of Energy intermediate ATP. This process consists of four stages: glycolysis, pyruvate breakdown, Citric acid cycle, and oxidative …show more content…
Glycolysis is regulated by feedback inhibition, causing a controllable process without deficiency or overexpression. It is good to mention that glycolysis happened with the presence or the absence of oxygen. However, in some cases, due to mutation or a damage in the mitochondria, Glycolysis rate increase dramatically despite the presence of oxygen, without moving to other pathways, and the formation of lactic acid, in a process called aerobic glycolysis. In this assignment, I will discuss the relation between glycolysis, its enzymes, and the formation of tumor cells in lungs, causing lung …show more content…
The human body undergo a process of cellular respiration to produce energy intermediates like ATP. Glycolysis is what the cell start with outside the mitochondria and it is the key in which the cell can continue an efficient production of ATP. However, the mutations and alterations of enzymes in glycolysis lead to aerobic glycolysis, which lead to an excessive amount of glucose uptake and production of lactic acid, promoting tumor cells and abnormal cell division that causes cancer. Lung cancer is widely spread and its one of the examples of Warburg effect. It has different types and can be treated by radiation or chemicals. However, cancer treatments nowadays are very risky and have severe side effects such as blood clotting, bone issues, and hair loss. More efforts should be put in the deeper understanding of glycolysis and other pathway. In addition, it would me more efficient to find other treatments with less side effects that target the stage of glycolysis in tumor cells, inhibiting the overexpressing of enzymes and the production of lactic, leading to stop the abnormal cell division, and cure