Dear Respected Karolinska Institute admission committee,
I am writing to express my interest in “studies of angiogenesis and vessel malformation and function, relating to genetic vascular disease, cancer, diabetes and stroke” at Karolinska Institute.
I graduated master degree in Human Genetics in the Shahid Beheshti University of Medical Science, the second-ranked medical university in Iran, working on cancer research. While there is no similar outstanding Ph.D. position in this field of study, in Iran, I want to apply to this position for I believe my strong academic background and extracurricular interests makes me a good fit for the position.
As a Genetics major, I have a deep-seated curiosity about discovering new cancer treatments. Unfortunately, to date, there are no approved cancer treatments, which is why I am interested in the pioneering cancer discoveries made by Karolinska Institute and their potential to
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To fulfill my goal, I decided to study Molecular and Cell biology in college in 2013 to be eligible for entering M.Sc. degree in Human Genetics program. This major was a great opportunity to get familiar with the great importance of medical genetics with regard to cancer in years to come. Through the course and after some research on the key signaling pathways in breast cancer, I decided to target HIF-alpha signaling pathway in TNBC cancer cell lines as my thesis project. The results were desirable for our investigation and we could suggest the pathways by which our bacterial supernatants targeted. Thereafter, I got familiar with system approach in reconstruction and analysis of key pathways involved in exacerbation of the chronic obstructive pulmonary disease (COPD). I got well familiar with pathway identification and construction to narrow down underlying targets for possible future molecular