Fix or replace damaged tissue; biology has always been the main concern for scientists. Today, the most important instrument for tissue engineering scientists to produce replacement tissues and implants to repair or replace damaged tissue. Tissue engineering is generating a new field of study in which the principles of engineering and biology to correct the damaged tissue, uses and can renewal, operation and maintenance of tissue healing.
In order to use an ideal scaffold Tissue engineering should have features such as non-toxic Cell and tissue properties to be fit. About, bone tissue engineering Biological properties and mechanical properties is very important.
On the other hand, for mimicking natural bone, as possible, composition and structure are similar.
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In mechanical terms, the scaffold must be capable, weight bearing on the duration of the demolition and replacement of tissues, because it is, primary tissue produced, the process of regeneration, very soft and flexible and are easily transformed.over time, this tissue, more strength, finds that at the same time, by dissolution scaffolding and on the other hand, the mechanical properties of scaffolds, bone, should not be a big difference, because it leads to stress concentration and lack of regeneration and degeneration leads to healthy tissue.
In this respect, nanotechnology and in particular electrospinning as the production technology of Nanofibers has been of interest to scientists, nnanofibers the perfect pick for the purpose of natural extracellular matrix, in vitro.
Due to the propinquity of the construction in the structure of fibrous tissue and extracellular matrix and as well as highly effective surface for adhesion and growth of cells, research on this scaffold are