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Haemolytic Anemia Causes Rbc Failure

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Anaemia is defined as impairment of the oxygen-carrying capacity of the blood. It can be classified based on the underlying causes or the morphology of red blood cells (RBCs). Blood loss, which can be acute due to trauma and chronic due to iron deficiency will reduce the amount of RBCs, leading to anaemia. Anaemia can also be caused by increased RBCs destruction, termed haemolytic anaemia. Haemolytic anaemia can be inherited or acquired later on. In inherited condition, deficient haemoglobin production results in α-/β-thalassaemia. This leads to RBCs production that are hypochromic and microcytic, which are later destroyed. Structurally abnormal haemoglobins produce sickle-shaped cells will then be rapidly haemolysed, as seen in sickle

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