Aim
This experiment separates the constituents of a commercial headache powder employing the use of extraction method. The active ingredients of the commercial headache powder were extracted by dissolving the powdered tablet in propanone solvent. The suspended fine particle binders in the propanone solution were removed by filtration method. The solid analgesia was obtained by evaporating propanone solvent. It was then collected on Hirsh funnel by filtration. Melting point determination was performed to test for the purity of the drug (tablet).
Hypothesis
It was hypothesized that crude paracetamol melts at 165.1℃ while pure paracetamol melts at 170.5℃.
Background information
Paracetamol is a commonly used medicine. It is known as a mild
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On the other hand, white solid paracetamol, 100ml beaker, and 15ml of hot water, 20ml warm water, and water bath were used for the recrystallization purification technique. Evaporating dish, cold water, stirring rod, watch glass, small beaker, oven, cotton wool, and tissue were also employed in the recrystallization purification method.
Method
Recrystallization purification technique A portion of crude paracetamol sample was transferred into a 100ml beaker. To it, 10ml of hot water was added to dissolve it. Cotton wool was placed into the funnel; this was followed by pouring hot water onto the cotton wool before filtering the dissolved paracetamol crude solution to remove any insoluble materials. Watch glass was placed on beaker containing filtrated solution and the solution was allowed to cool slowly. After the filtrated solution had cooled up, it was placed into a beaker containing cold water. The corners of the beaker containing filtrated were scratched to allow the crystals to form. The purified paracetamol was collected by filtering through a funnel containing cotton wool. The obtained paracetamol crystals were dried by blowing air through them for fifteen minutes. The resulting product was placed into a small beaker, covered with tissue paper and then placed into the oven to dry further. After paracetamol crystals were completely dried up, the paracetamol crystals were taken out of the oven, followed by determining their melting points (Kilway