Biological theories of aging and its genetic control by Micro-arraying mortality
Mottadi Shiva
Abstract
Aging is due to progressive physiological changes in an organism that lead to decline in biological functions. Several theories that fall into mainly two categories that is both programmed theories and damage or error theories. These theories have been proposed to explain the process of aging, but they don’t appeared to be fully satisfactory. These two theories may interact in a complex way with each other. To promote successful aging that is possible by understanding and testing the existing and new aging theories. It may be possible to promote successful aging as well as to enhance the lifespan of mankind by understanding and testing the
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An interesting Geronto-gene that provides a little insight to the mechanics of ageing is DAF-16.
Keywords- Programmed theories, Geronto-gene, Longevity, DNA microarray
Introduction
The Aging process takes place in a cell or an organ or the total organism with the passage of time. Studying the psychological, social and biological aspects of aging process is known as Gerontology. Gerontology can be expressed in mainly three aspects that can be Longevity (span of life of an organism), Aging (sequential or progressive change in an organism that leads to an increased risk of debility and disease), and Death. There are many questions that are often pondered by the mankind in the past couple of hundred years like Why do we age? When do we start aging? What is the aging marker? Is there a limit to how old we can grow? There are many theories that had been proposed that explains the process of aging, but none of them appears to be satisfactory completely- Dr. Davidovic et al. Several Biological theories of aging that fall into mainly two categories that is either A) Genetic theories/programmed theories or B) Non-genetic theories/damage or error