Lymphoma comprises a histologically heterogeneous group of cancers arise from the cells of the immune system with enlargement and propagation of lymph nodes or secondary lymphoid tissues.(1)." About 54 percent of the blood cancers that occur each year are types of lymphomas", The main types of lymphomas are Hodgkin lymphoma and non-Hodgkin lymphoma. non-Hodgkin lymphoma is a cancer that starts in cells called lymphocytes , which are part of the body’s immune system.
There is different signs and symptoms can caused Non-Hodgkin lymphoma , it depending on where it is in the body for example: Fever, Weight loss, Night sweats, extreme tiredness ,anemia , Enlarged lymph nodes, Swollen abdomen (belly), Feeling full after only a small amount
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If signs or symptoms suggest that a person might have non-Hodgkin lymphoma, exams and tests will be done to find out for certain if they do and, if so, to determine the exact type of lymphoma.
Lymphoma can come in three ways, unifocal, multifocal, or diffuse, and affect isolated lymph nodes or any organ in the body, and demonstrate a range of imaging appearances at almost every site. The unaffected lymph nodes often have an elongated shape and a fatty hilum(1)
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3-CT
It is radiological exam that uses x-ray tube to produce cross sectional images of the body by rotating around it and detecting the radiation coming out of it. This modality able to provide internal soft tissue details so it asses to reveal if any lymph node or organ are enlarged. CT are helpful in looking for any lymph in abdomen, pelvis, chest, head, and neck(2). and hepatosplenomegaly, or filling defects in the liver and spleen.
CT is used for initial staging, assessing response to therapy , and for follow-up.(3)
Positron emission tomography or pet, it is an advanced tomographic functional imaging modality. This technique depends on detecting gamma ray produced by radio tracer like 18 F "FDG" flouro deoxyglucose through pair production resulting in a pair of gamma-ray each with 511 Kev energy an 180° "add picture of annihilation event ".
The uptake mechanism of FDG depends on the metabolism rate of the cell whether it was organ, muscle or a tumour cell.
Using this modality technique can help us to accurately diagnose and evaluate re-evaluate patient after