ipl-logo

Nucleocapsid Summary

1368 Words6 Pages

To analyze the dynamics of nucleocapsids (NC) in replication, live-cell imaging is studied as a possible method to express. This method will allow scientist to get a better understanding of the significance of the nucleocapsids through fluorescent labeling. Through reverse genetic systems allows virus like Marburg and Ebola proteins to be expressed. However there have been cases that's difficult to see filo viral nucleocapsid properly due to its limited size. Researchers hypothesized that the VP30 an essential protein and a structural component can allow visualization of NC (Schudt et al., 2013).
Scientists were curious about where NC became linked with VP40 a matrix protein. Since VP40 has the ability to suppress the Marburg replication, …show more content…

The most commonly used test is called Enzyme-linked immunosorbent assay or ELSA testing which is a highly sensitive and accurate that uses the components responsible for the immune system to see if the immune system is responding properly. The test contains an Antigen-capturing enzyme that detect mainly proteins however the test can successfully detect hormones, foreign antigens and antibodies. They are different ways that ELSA test can be performed, the most essential way of conducting the test is basically attaching an antigen to an antibody. The antibody favors a specific substance that it wants to be attached to and if the substance is attached to the antibody chances are that the patient is infected (Med. Net, …show more content…

The blood specimens collected were put at a temperature at −80°C. The samples from the patients were moved to more established laboratories that can work on fatal agents. The results of the agents collected revealed that that the contagiousness was fairly low there were only a few cases that was recorded for secondary infection. Rudolf Siegert and Hsin Lu Shu continued with the Guinea pigs by the third passage the animals have completely exhibit all the symptoms such as fever and hepatitis and eventually died later. Nonetheless, they weren’t able to detect the agent precisely but the results of the experiments were groundbreaking and proved that the virus can be passed and have similar effects from one individual to another (Slenczka, Klenk

Show More
Related
585 Words | 3 Pages

As soon as Gey realized what he had discovered he ordered a large factory to be built to mass produce HeLa cells, its main purpose was to discover a cure for Polio (Skloot, Pg. 93), but not only did it provide aid in the medical world, but companies such as cosmetic corporations could test the effects of their makeup and other cosmetics on cell health (Skloot, Pg. 102). The possibilities of research with HeLa cell were endless, anything from the research on atomic radiations effect on cells and how to reverse the damage, to the discovery of cells being able to live on after the extraction of their nucleus, and even the vast amount of studies of chemotherapy drugs, hormones, vitamins, and environmental stress proved the importance of HeLa cells in modern research (Skloot, Pg. 102). For the first time ever, scientists were able to properly identify the correct number of chromosomes and map them out, this further lead to the ability of being able to diagnose diseases where individuals had an excess or lack of chromosomes such as Trisomy 21 or Klinefelter syndrome (Skloot, Pg. 100). The science world had finally found a way to overcome the expense and strenuous procedures to obtain cell subjects, scientist could test the effect of gravity, the pressure of deep sea diving by spinning the cells in a centrifuge (Skloot,

Read More
573 Words | 3 Pages

Jonas Salk was able to develop a polio vaccine through his work with the cells. HeLa cells also led to the discovery of an influenza vaccine. The research on these immortal cells did see quite a bit of turbulence in the scientific community, though. When Stanley Gartler announced that HeLa cells had contaminated many other cell lines thought to be unique in 1966, many scientists became outraged and questioned the preposterous accusations. Even more controversial was the exposure of malpractice within the realm of cell research.

Read More
1249 Words | 5 Pages

In The Immortal Life of Henrietta Lacks, Rebecca Skloot presents study cases, such as the study of vaccines and the polio vaccine to prove that HeLa cells have benefitted science for the greater good. The benefits of HeLa cells are shown when the Polio and HPV vaccine is talked about. The polio vaccine benefitted the human race by saving lives and impacted science by progressing further studies. Further studies included the HPV vaccine which gave scientists a vast knowledge on how cancer forms and how it is inserts insert into DNA. It is later proven that the study of Virology is the cause of scientists advanced experimentation with cancer and expanded their boarders with the topic.

Read More
348 Words | 2 Pages

This study was passed and funded through Congress; however they did not know the full story. The wrong in this study was that the men did not give informed consent and did not receive any treatment. The men were studied till their autopsy, which is obviously death. This sparked much controversy and changed human experimentation forever.

Read More
978 Words | 4 Pages

1. Briefly describe how phage were discovered, and how they were quickly used to treat disease. a. Phage were discovered by Felix D'Herelle when he found a motive to search of a "good microbe hunter" after seeing 20 people dead in 8 days due to the yellow fever. He originally discovered phage by chance. While working with sick locusts, he observed a puzzling phenomenon: amid some of his bacterial cultures, there were what he described as "taches vierges" - pure or clear spots on an otherwise cloudy background.

Read More
785 Words | 4 Pages

For example, on page 94, Nancy Jaax realizes that Ebola can be transmitted through air, “It probably traveled through the air in aerosolized secretion. That was when I knew that Ebola can travel through the air.” However, on page 95, it goes to Mr. Yu G., a victim of Ebola, and how he died from it, “ Yu. G. went into shock and died with blood running from the orifices of his body … Mr. Yu. G. was the first identified case, the index case, in an outbreak of an unknown virus.”

Read More
416 Words | 2 Pages

C. If the scientist find out how the disease was transmitted then they could control it. D. The scientists observed different patterns of the victims. They also needed to retrace each of the victims steps, to find what each of the victims had

Read More
1870 Words | 8 Pages

He and Jahrling begin analyzing the sample of the monkeys’ blood serum which was wrongly diagnosed. During the procedure, there’s a part where the scientists decide to smell it without knowing it’s infected or not. If the virus was airborne, both of the scientists would have infected. Chapter 13 Thanksgiving: The Jaax Family visits their family over Thanksgiving.

Read More
761 Words | 4 Pages

The experiments performed by German physicians during World War II were torturous, unethical, and unreasonable when considering better ways in which the research could have been conducted. Experiments were performed on non-consenting camp prisoners by physicians attempting to improve soldier survival rates and further knowledge in lesser-explored medical fields (Coleman et al. 16). Experimentation to find a cure for Malaria was performed from February 1942 to April 1945, during which time prisoners were infected with malaria and treated with different drugs in order to find the best cure. Coleman notes, “Over 1,000 involuntary subjects were used in these experiments. Many of the victims died and others suffered from severe pain and disability…”

Read More
510 Words | 3 Pages

The doctor who tried to cure him of this virus also experiences the same symptoms as Monet and almost is killed the same way. He soon recovered and everyone in the building was checked to make sure they were healthy. Around 4 years later a women named Nancy who is a pathologist who studied the

Read More
1348 Words | 6 Pages

Edsall believes that what Krugman is doing is beneficial to the child. By doing this study it helps inform and control the infection than an untimed uncontrol one. Edsall mention that this study has been repeatedly and carefully examined and verified. Edsall is its not a proper and ethical to have the experiments on children in which would not create greater risk than having it run through nature. Its better if the child is artificially infected than having nature infected

Read More
1089 Words | 5 Pages

In the 1950s, American Opinion Polls noted that a polio epidemic was `second only to the atomic bomb', and that polio was `the thing that Americans feared the most’. The polio virus, an infectious viral disease that attacks the nerve cells and the central nervous system, has caused many epidemics in the past. When the virus affected President Franklin Roosevelt, many researchers and scientists began to study the virus and (adj) search for a cure. As a result of this research, many discoveries and breakthroughs were made within the medical field. Two great scientific leaders, Jonas Salk and Albert Sabin, emerged and inspired further research.

Read More
1015 Words | 5 Pages

Some of the infected men passed on the infections to their wives, who then passed it onto their

Read More
452 Words | 2 Pages

This was the time when the intervention in the photo 1 was implemented in the early 1900s. From the photo, it is clear that the public health authorities focused on the biomedical perspective. They have clearly stated how the disease was transmitted and how to stop the transmission. In the late 20th century, different perspectives of public health were applied on different continents.

Read More
871 Words | 4 Pages

On July 2nd, Jonas Salk tried the polio vaccine on children who had already had polio and had recovered from it. After he saw that it worked then he tried on people who had not ever had polio like himself, his wife and even his kids. All of the volunteers produced antibodies and none of them ever got sick. On February 28, 1953, James Watson and Francis Crick announced that they had discovered the double-helix, which contains human genes.

Read More

More about Nucleocapsid Summary

Related Topics

Open Document