ipl-logo

Heterocyclic Compounds Research Paper

1044 Words5 Pages

5-membered rings containing heteroatom11
One hetero atom11 Figure 1.3: Structure showing the heterocyclic compound having one hetero atom
Two hetero atoms Figure 1.4: Structure showing the heterocyclic compound having two hetero atoms
6-membered ring containing heteroatom11 Figure 1.5: Structure showing the six membered heterocyclic compounds
Unsaturated and saturated heterocyclic compound12 Figure 1.6: Structure of saturated and unsaturated heterocyclic compounds

1.7 AZOLES
Azoles are the class which contain five member ring, having nitrogen heterocyclic ring compound containing at least one other heteroatom (or non-carbon atom) of nitrogen, sulfur or oxygen and are considered to be derived from pyrrole, furan and thiophene by substitution of methane groups (―CH=) by pyridine type nitrogen (―N=) atoms from the different positions. Azole mainly consists of:
(i) Oxygen is referred as oxazole
(ii) Sulphur is referred as thiazole and
(iii) Nitrogen is referred as pyrazole, imidazoles or imidazolines12.
1, 3-Azoles synthesis12

Scheme 1.1: Synthesis of 1, 3-Azoles by Cyclodehydration of α-acylaminocarbonyl compound12
1.8 OXAZOLE …show more content…

During the world war when penicillin was considered to contain the oxazole ring system at that time the chemistry of oxazole was come in concern, but the invention of oxazoles as dienes in Diels-Alder reaction and in 1, 3-dipolar cycloaddition reaction of mesoionic heterocycles give idea for progress of oxazole chemistry. Oxazole contain an oxygen atom and a pyridine type nitrogen atom at the 1 and 3 positions of the ring and like pyridine, oxazole are weekly basic substances. Oxazole be considered as derived from furan by the replacement of –CH= (methane group) from the position-3 by the azomethine nitrogen (-N=) group13. Oxazole ring is numbered as

Show More
Related
779 Words | 4 Pages

Benzyne Formation and the Diels-Alder Reaction Preparation of 1,2,3,4 Tetraphenylnaphthalene Aubree Edwards Purpose: 1,2,3,4-tetraphenylnaphthalene is prepared by first producing benzyne via the unstable diazonium salt. Then tetraphenylcyclopentadienone and benzyne undergo a diels-alder reaction to create 1,2,3,4-tetraphenylnaphthalene. Reactions: Procedure: The reaction mixture was created. Tetraphenylcyclopentadienone (0.1197g, 0.3113 mmol) a black solid powder, anthranilic acid ( 0.0482g, 0.3516 mmol) a yellowish sand, and 1,2-dimethoxyethane (1.2 ml) was added to a 5-ml conical vial.

Read More
469 Words | 2 Pages

In this lab, three unknown compounds were separated from a mixture and identified by melting point. Unknown mixture #124 has components of acid, base and neutral compound. The compounds were identified by melting point and matched up with the known melting points from a given list. In order to identify the compound it was important to separate by dissolving the mixture in an organic solvent which was not soluble in water, and then extracting the solution first with HCl, and then dilute sodium hydroxide solution. From the separation mixture, the aqueous layer were obtained and labeled as TT-1 (base), TT-2(acid) and TT-3 (neutral) in three different test tubes for later recovery.

Read More
163 Words | 1 Pages

The discovery of chlorpromazine in 1953 was the main historical milestone in the field of psychiatry. This is not only because chlorpromazine was the first drug that cured symptoms of psychosis; but it also provided clues to identify the biological basis of psychotic disorders like schizophrenia, because of its action on dopamine receptors. After the discovery of chlorpromazine, a lot of antipsychotic drugs were identified to treat psychotic symptoms. Followed by chlorpromazine, other phenothiazines including perphenazine and fluphenazine were introduced.

Read More
996 Words | 4 Pages

Moreover, Penicillin, a group of antibiotics, was discovered during this time, specifically in the 1928s by Alexander Fleming (ACS, 2023). Although the first dose of penicillin was used in 1941 by Albert Alexander, it was still a life-changing discovery as it changed the lives of many - even after the period of 1918s1939s (Wood, 2010). The discovery of penicillin allowed a lot of life-threatening diseases to be treated, such as bronchitis, tonsillitis, and pneumonia. Penicillin is known to save millions of lives. Indeed, in just World War Two, the death rate because of bacterial pneumonia would go from 18% to 1%, because of the invention of penicillin.

Read More
285 Words | 2 Pages

If you’re like me, you love nothing more than getting your feet wet at the ocean. But what if every time you stuck your feet in you were greeted by brackish water? That’s our world if we don’t change. When Oxybenzone, the active ingredient in 70% of suntan lotions, meets coral reefs, only trouble happens.

Read More
1014 Words | 5 Pages

Amid Alexander Fleming 's Nobel discourse he said, "After I finished my research, biochemist Dorothy Crawfort Hodkin used x-rays to determine the atomic structure and molecular shape of penicillin. " (Fleming,2)Dr. C.G. Paine, dermatologist Albert Nutt were two famous doctors who used Hodkin’s research to develop several startling cures with the new substance as early as 1930 (Krebs,23) All of the fresh out of the box new research and the newfound properties of penicillin brought these new anti biotics which cured maladies that were very common, which balanced out various sorts of microbes. The life expectancy of the urban population increased by 3 years.

Read More
365 Words | 2 Pages

The greatest hero of World War II may come as a surprise. Penicillin is responsible for saving hundreds of thousands of lives from infectious diseases during the war. Penicillin took a while to become a widely used medicine, but its effects were revolutionary. To lead off, the first discovery of penicillin was made by Alexander Fleming. This monumental discovery happened to have been found and created by accident.

Read More
520 Words | 3 Pages

Many people do not realize that chemistry is a part of our day to day lives. One specific thing we see on a daily basis is the colors and paint people use in paintings, on buildings, and any other place paint could be. When this paint is developed, the people who make it have to decide exactly what the compound should be made up of. This is an important thing to consider when making these paints because as discussed in Chemistry 101 lab, compounds are different things that develop one item, in this case it is paint. They have to make sure that the paint is homogenous because if it was heterogeneous when being applied, the paint would not go on well.

Read More
889 Words | 4 Pages

Penicillin is an antibiotic which is made from the mould from Penicillium. Penicillium is a fungi which is found naturally in soils, wood, plants etc. (Frisvad & Samson, 2004). During the early 20th century a scientist by the name of Alexander Fleming discovered the effects of the Penicillin. (Dougherty & Pucci, 2011)

Read More
158 Words | 1 Pages

In September 1928, from Alexander Fleming’s accidental discovery and isolation of penicillin marks the start of modern antibiotics. Before that, several scientists had published or pointed out that mould or penicillium sample were able to inhibit bacterial growth, and even to cure bacterial infections in animals. Alexander Fleming was the 1st who push past studies further by isolating the penicillin and by being motive enough to promote his discovery at a larger scale. He also discovered that bacteria developed antibiotic resistance whenever too little penicillin was used or when it was used for too short a period. Alexander Fleming cautioned about the use of penicillin in his many speeches around the world that not to use penicillin unless

Read More
1032 Words | 5 Pages

Therefore penicillin was just an afterthought, until Howard Florey and Ernst Chain turned it into the lifesaving drug is today, twelve years after the initial discovery. In 1939 Florey and Chain began working with penicillin and trying to make larger quantities by fermenting the mold in everything from baths to food tins( Aldridge par 4). The pair tested the effects of penicillin on a police officer with an infected cut on his face, he made a remarkable recovery. But nonetheless he died once the supplies of penicillin were depleted. This test caught the attention of pharmaceutical companies from either side of the pond took interest on this “wonder drug”.

Read More
630 Words | 3 Pages

During one of his experiments, Alexander Fleming noticed a bacteria free ring in a plate of staphylococci bacteria. In the middle of the ring was a type of mold that had accidentally developed (“Sir Alexander Fleming”). He named the mold penicillin and used it to create antibiotics. These drugs cured and prevented deaths from bacterial infections such as meningitis, syphilis, and gonorrhea. The Allies during World War Two made sure the drug was readily available during the D-Day Invasion of Normandy.

Read More
920 Words | 4 Pages

To analyze the acetanilide product of the reaction, 1H NMR and IR were used. Results, Discussions, and Conclusions In this experiment, acetanilide was synthesized via nucleophilic acyl substitution from both acetic anhydride and aniline. During this reaction, aniline acts as the nucleophile and acyl (CH3CO-) group from acetic anhydride acts as the electrophile.

Read More
1148 Words | 5 Pages

Introduction Chevron Phillips Chemical Company is the major producer of Cyclohexane. This successful company hoses the three largest cyclohexane plants in the world. Many are puzzled by how the production of cyclohexane seems to have become stagnant. Perhaps this is due to the cost of benzene increasing or the demand increasing. Through thorough investigation, the answer to this question and many more can be answered.

Read More
831 Words | 4 Pages

Halogens belong to group 7 in the periodic table, and are non-metallic elements. The term halogens mean “Salt former” which means that their combinations containing halogens are called Salts. All halogens have 7 electrons in their valence shell, giving them a charge of -1, and only require one electron to become a complete shell. Halogens are very chemically reactive which increases as you move up the periodic table – fluorine being the most active element. Halogens exist in room temperature in all 3 states of matter; Solid (Iodine and Astatine), Liquid (Bromine), and Gas (Fluorine and chlorine), and is considered toxic.

Read More

More about Heterocyclic Compounds Research Paper

Related Topics

Open Document