ipl-logo

Flucloxacillin Research Paper

701 Words3 Pages

Flucloxacillin: - It is a member of the penicillin family that is used as an antibiotic for the staphylococcal infection (bacterial infection) that affects the human tissues of the skin and the lungs (pneumonia). It is also used in the treatment of food (rotten food) and poisoning of theblood. Staphylococcus may also be a risk to the human life if it releases its toxins by some strains of the bacteria to cause toxic shock. - Flucloxacillin is prescribed mainly in Australia & Europe, as it is very effective against the staphylococcus bacteria by inhibiting the synthesis of its cell wall then it will die. - Flucloxacillin is a ß-lactam antibiotic with a narrow spectrum. - Unlike the other penicillins, Flucloxacillin has an acitivity against …show more content…

 Possible modifications sites are in a square in the structure. The modification of the structure to produce Flucloxacillin is: Flucloxacillin has a bulky and electron-withdrawing heterocyclic acylamino side chain which is responsible for narrow-spectrum, β-lactamase-resistant penicillin, acid-resistant characters of the Flucloxacillin. Synthesis of Flucloxacillin: Overview about synthesis: 1- Firstly 3-(2—chloro,6-fluorobenzene)-5-methyl isoxazole-4-formic acid (raw material) reacts with Phosphorus oxychloride by using a Catalysis of organic amine to generate acyl chloride 2- After that dissolve 6-APA (6-aminopenicillanic acid) and inorganic alkaline in H2O. 3- Then add drops of an acyl chloride solution which was obtained from the first step. 4- Add HCl acid (acidizing agent) after completing the reaction. 5- layering; concentrating under a lower pressure, add residues into an alcohols solvent for dissolution, add drops of H2O to separate out flucloxacillin crystals 6- Then dissolve Flucloxacillin acid in an organic solvent. 7- Drip Na iso-octoate solution for reaction to produce a product, namely flucloxacillin sodium monohydrate. Step 1: Step 2: Step

Show More
Related
438 Words | 2 Pages

According to Joseph Castro a contributor from the website Live Science,” Methicillin-resistant Staphylococcus aureus, or MRSA, is a strain of staph bacteria that is resistant to the antibiotics normally used to treat such infections” (Castro 2013). Castro explains how in 1940 doctors started treating MRSA with penicillin. After penicillin doctors started using methicillin because penicillin helped the microbes evolve with resistance to penicillin. Then after penicillin methicillin became the new treatment for

Read More
544 Words | 3 Pages

If the diagnosis is uncertain, the text recommends antibacterial therapy if illness is severe, meaning AOM presents with moderate to severe otalgia or fever of 39°C (102.2°F) or higher. A high-dose amoxicillin at 40–45 mg/kg twice daily is the first treatment of choice due to its cost, taste, safety, and effectiveness. The duration of treatment depends on the patients’ age and the severity of illness and can range from 5 to 10 days. For patients with a penicillin allergy, drug selection process depends on the severity of the reaction (Burchum & Rosenthal,

Read More
996 Words | 4 Pages

Moreover, Penicillin, a group of antibiotics, was discovered during this time, specifically in the 1928s by Alexander Fleming (ACS, 2023). Although the first dose of penicillin was used in 1941 by Albert Alexander, it was still a life-changing discovery as it changed the lives of many - even after the period of 1918s1939s (Wood, 2010). The discovery of penicillin allowed a lot of life-threatening diseases to be treated, such as bronchitis, tonsillitis, and pneumonia. Penicillin is known to save millions of lives. Indeed, in just World War Two, the death rate because of bacterial pneumonia would go from 18% to 1%, because of the invention of penicillin.

Read More
1399 Words | 6 Pages

Tobramycin is an antibiotic, which works to fight off bacteria

Read More
396 Words | 2 Pages

Minoxidil 's main role is to stimulate the blood circulation of hair follicles, improve hair follicle. Here with the simply introduce a few basic knowledge when using cosmetic raw material minoxidil solution to cure the male hair loss. The initial hair loss: topical minoxidil solution can cause initial mild hair loss to increase, because minoxidil already in the telogen hair loss, usually on the scalp hair in the telogen last 100 days fall, 10% of hair in telogen increased to 20%, but in the area of male pattern baldness, shrinking of hair follicles in the telogen, when minoxidil work for thinning hair, can explain why Minoxidil can cause hair loss, hair fall will be the repose of the end of the thicker, healthier hair to replace the other hand, the treatment of male pattern baldness will result in hair follicles gradually narrowing. On minoxidil resistance, misunderstanding, minoxidil will help restore the hair follicles, again in about two years (sometimes years) to grow thicker hair, more than this

Read More
540 Words | 3 Pages

Yet, the first great pharmaceutical discovery of the 1920s addressed not an infectious disease but a physiological disorder. (Holley) Paragraph 5: Penicillin was rediscovered in 1928 by Scottish scientist Alexander Fleming, who noticed a halo of inhibition of bacterial growth around a contaminant blue-green mold on a Staphylococcus culture. Fleming concluded that the mold was releasing a substance that was inhibiting bacterial growth. He grew a pure culture and discovered that the fungus was Penicillium notatum, he later named the bacterial inhibiting substance penicillium after the Penicillium notatum that released it. (Jody)

Read More
1770 Words | 8 Pages

Polymyxin B is effective against gram-negative bacteria. It is available for topical use in the antiseptic ointment that also contains bacitracin and neomycin. Rifampin, is used in tuberculosis therapy. The drugs inhibit the synthesis of mRNA. The first of the quinolone group was nalidixic acid, which inhibits the enzyme DNA gyrase needed for DNA replication.

Read More
219 Words | 1 Pages

Today I will be talking about MRSA. MRSA is short for Methicillin Resistant Staphylococcus Aureus. MRSA is also known as a Superbug. I will tell you why it 's a Superbug, how it 's treated, and a method of prevention. This is a bacteria that will cause you to have an infection.

Read More
1037 Words | 5 Pages

However, the amount of Staphylococcus aureus that is antibiotic resistance gradually increased, until the year of 1950, the number rose to 40% of the patients, and 80% of the patients until the year 1960. The mechanism that made the bacteria become resistant to the antibiotic is that, a mutation to an extremely small amount of Staphylococcus aureus. From this mutation the bacteria began to produce an enzyme called penicillinase, which it breaks the molecule within penicillin that makes the antibiotic to function. Consequently, this antibiotic become ineffective and the bacteria eventually survived. This kind of Staphylococcus aureus is called “MRSA”, referred to methicillin-resistant S. aureus.

Read More
627 Words | 3 Pages

Unfortunately, carbapenem antibiotics often are the last line of defense against Gram-negative infections that are resistant to other antibiotics.

Read More
1635 Words | 7 Pages

Methicillin Resistant Staphylococcus Aureus Methicillin Resistant Staphylococcus Aureus (MRSA) is a bacteria resistant to all antibiotics containing penicillin. MRSA otherwise known as a superbug has been produced through the process of natural selection inside hospitals, which provide the perfect environment for this bacteria to thrive in. Bacteria like MRSA are hard to treat as there are fewer antibiotics to treat it therefore increasing its deadliness. The antimicrobial resistance in MRSA is genetically based, meaning that it can spread its immunity amongst other bacteria by horizontal gene transfer. MRSA is a bacteria that can withstand antibiotics containing penicillins.

Read More
594 Words | 3 Pages

Baclofen, simply means “muscle relaxer” & an antispastic agent. Baclofen is used for treating symptoms in muscles like multiple sclerosis - including spasm, stiffness and pain. This drug is also used for many purposes that are not listed in this guide Baclofen very rarely causes serious side effects. However, if you experience symptom of serious side effect do not hesitate to call the doctor. Serious side effects: A serious allergic reaction to this drug is rare.

Read More
856 Words | 4 Pages

Part 1: What Is Cephalosporin? How Do They Work? Cephalosporins consist of a group of semisynthetic antibiotics with a broad-spectrum of activity. They are derived from fungi called Cephalosporium, which are known to inhabit soil and

Read More
825 Words | 4 Pages

The final two antibiotics examined, penicillin and tetracycline, may stay relatively close to each other in relation to the percentage of cases in which they are used and have found to be

Read More
1737 Words | 7 Pages

Antibiotic prophylaxis Anthrax can be treated in its earliest stages with penicillin (often delivered intravenously), tetracycline, ciprofloxacin or doxycycline. Evidence of antibiotic effectiveness comes from use in human and animals infected with Bacillus anthracis. Antibiotics related to ciprofloxacin including chloramphenicol, erythromycin and some cephalosporins were also found to be effective. The antibiotic treatment is highly effective in early stage of the disease and becomes largely ineffective in later stages with severe complications.

Read More

More about Flucloxacillin Research Paper

Open Document