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Summary: Joint Damage

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2. Why would joint damage be associated with rapid growth and low testosterone levels?

The reason Eric could be experiencing joint damage from rapid growth and low testosterone is due to the role testosterone has on bone. Testosterone is responsible for bone density and maturation. If Eric is growing too quickly due to excess GH and not producing enough testosterone due to low LH and FSH then he would experience low bone mass. Testosterone is also responsible for the hardening of the ends of the bones. When the ends of the bones are not hardening as they should due to rapid growth and low testosterone the result is joint damage. This would explain why Eric’s doctor could not find a cause to his joint damage when they removed 500cc’s …show more content…

Why are his kidneys so active at night? Note: diabetes insipidus is not diabetes mellitus, so the answer is not high blood sugar levels or an insulin deficiency. Diabetes merely means high urine production. Look for a specific hormonal problem involving the pituitary. What hormone would
Dr. Lee have prescribed?

Central Diabetes Insipidus is caused by a lack the Antidiuretic Hormone (ADH) or Vasopressin produced by the hypothalamus and secreted by the posterior pituitary gland. ADH is responsible for the amount of water excreted by the kidneys. If ADH is low or not being secreted then the kidneys do not function properly and excrete too much water. This is why it is termed Central Diabetes Insipidus, because the problem lies in the pituitary gland and not in the kidneys which is termed nephrogenic diabetes insipidus.
Dr. Lee should prescribe the hormone Vasopressin (Desmopressin or DDAVP) which can be given by nose spray, injections or tablets. Vasopressin should help to regulate Eric’s urine output and help maintain his fluid balance.

https://www.nlm.nih.gov/medlineplus/ency/article/000460.htm

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