ipl-logo

Synthesis Synthesis Preparation

705 Words3 Pages

Experimental and Methods Materials All chemicals and solvents used in this study such as hexane, ethanol, hydrogen peroxide, toluene and acetic acid were analar grade and were used without further purification. Oleic acid (OA), Linoleic acid (LA), p-toluenesulfonic acid (PTSA), oleyl alcohol (OL) and oleoyl chloride (OLC) were acquired from Fisher and Merck. Synthesis Reactions Monoepoxidation of Linoleic Acid (MELA) (2) Linoleic acid (LA) 1 (1.4 g) was fluxed in 10 mL toluene and 120 mg of Novozym 435® lipase was added to the solution. During stirring the reaction for 15 min, 30% H2O2 (15 μL) was added and the addition was repeated every 15 min for 7 h. after complited the reaction the lipase Novozym 435® was filtered and the mixture of …show more content…

The mixture was heated at 110 ºC and for 7 h. The mixture was washed with the water and was dried by using anhydrous sodium sulphate [18]. Synthesis of oleyl 9,(12)-oleoyloxy-10,(13)-oleioxyoctadecanoate (OLOLOODT) (5) OLHYOODT 4 (2.5g; 0.003 mol), pyridine (1.66 g; 0.002 mol) and CCl4 (10 mL) were mixed and heated at 60 °C. OLC (16.2 g; 0.013 mol) was adding during 1 h, and the reaction mixture was refluxed for (5.5 h). The mixture was washed with the water and was dried by using anhydrous sodium sulphate [19]. Characterization FTIR and 1H and 13C NMR FTIR of the products was recorded on a Perkin Elmer Spectrum GX spectrophotometer in the range 400-4000 cm-1. FTIR was used to measure functional groups of the synthesis products. A very thin film of products was applied to NaCl cells (25 mmi.d × 4 mm thickness) for analysis. 1H and 13C NMR analysis was performed with NMR spectroscopy model Joel FCP 400 MHz with the solvent CDCl3. 1H and 13C NMR of the products were recorded on a Bruker 300 NMR spectrophotometer

Show More
Related
382 Words | 2 Pages

The yellow solution containing the reactants was slowly poured into the beaker containing the cold water and the acid in order to cause the precipitation of the alcohol, 9-fluorenol and to destroy (hydrolyzed) the unreacted excess sodium borohydride. Subsequently, the white precipitate was vacuum filtered and washed twice with 20.0 ml portions of distilled cold water by pouring the liquid into the Buchner Funnel during filtration. It was necessary to wash the alcohol prior to recrystallization considering that the C-OH bond is easily broken by the formation of a stable and benzylic carbocation that favors the synthesis of difluorenyl ether. Finally, before the purification by recrystallization of the obtained product, the white solid alcohol was allowed to dry over a period of a

Read More
432 Words | 2 Pages

When the NMR spectrums for the standard and synthesized product were compared, similar peaks were observed as well. One small peak at 2-3 ppm and one large peak at 7-8 ppm was present. These similarities in spectrum patterns implies that the target molecule, triphenylmethanol, was indeed synthesized and was relatively pure. This conclusion was further supported by the product’s melting

Read More
840 Words | 4 Pages

The purpose of this experiment is to perform a two step reductive amination using o-vanillin with p-toluidine to synthesize an imine derivative. In this experiment, 0.386 g of o-vanillin and 0.276 g of p-toluidine were mixed into an Erlenmeyer flask. The o-vanillin turned from a green powder to orange layer as it mixed with p-toludine, which was originally a white solid. Ethanol was added as a solvent for this reaction. Sodium borohydride was added in slow portion as the reducing agent, dissolving the precipitate into a yellowish lime solution.

Read More
1332 Words | 6 Pages

Tyler White CHEM151LL 32658 04/01/2018 Different Types Chemical Reaction Types and Equations Purpose: The purpose of this lab experiment is to examine different types of chemical reactions such as Decomposition reaction, Synthesis reactions, Combustion reactions, and different Chemical equations. The experiments were conducted online using Late Nite Labs. Materials: Because the experiments were conducted online there wasn’t any physical use of materials, only digital ones, for these labs to be performed. Only the registration for the website was needed to perform these online labs, as well as a desktop computer.

Read More
588 Words | 3 Pages

The purpose of this experiment was to prepare an unknown Grignard reagent and then identify the product by molecular weight and melting point. An IR reading was taken to further identify and validate what product was formed. DISCUSSION AND CONCLUSION Organometallic compounds consist of a carbon that is attached to a metal. The carbon atoms are strongly nucleophilic because of a partial negative charge that they carry.

Read More
774 Words | 4 Pages

In 1997, Howarth and his group80 reported first, the asymmetric Diels-Alder reaction by using dialkylimidazolium salts (chiral and achiral) as efficient organocatalyst between crotonaldehyde or methacrolein and cyclopentadiene. The enentiomeric excess was less than 5% and no such diastereoselectivity were observed. Here enantiomeric excess did not depends upon the ionic liquids chirality, both chiral CILs and achiral CILs gave the near about same results. After that time researchers have been tried to design and synthesized Lewis acid based

Read More
1029 Words | 5 Pages

Intro: Chemical reactions are the foundation for all organisms to exist. Paragraph 1: Endergonic Anabolic Reactions Building Consumes energy to build complicated molecules from simpler ones Uphill Photosynthesis Uses water and carbon dioxide to create sugar and oxygen Protein synthesis from amino acids Dehydration reaction Monomers are covalently bonded to each other through the loss of water Bonds are created which means energy is used Endergonic Exergonic Breaking Release energy by breaking down complex molecules to simpler molecules

Read More
404 Words | 2 Pages

In our initial experiments, a 19% yield of 3,4-dicarbonyl substituted furan 3a was obtained when α,β-unsaturated carbonyl (1a) and 1,3 diketone (2b) were employed for the reaction (Table 1, entry 1) in a 1:2 molar ratio in the presence of 10mg of CuO-NPs in EtOH at room temperature without any oxidizing agent. When molar ratio of the reactants 1a and 2b were increased to 1:3, an improvement in the yield to 28% was observed (Table 1, entry 2) and molar ratio 1:5 gives the highest yield in the same reaction conditions 38% (Table 1, entry 3). The polar solvent such as DMF, DMSO, H2O, Xylene also gave the desired products but in low yield, while no reactions occurred in acetonitrile, toluene (Table 1, entries 4−9).When we employed a mixture of solvent EtOH: H2O (4:1) slight increase of yield 46% was obtained (Table 1, entry 10), increasing the mixture of solvent ratio to 2:1give the yield 51% (Table 1, entry 11) and solvent ratio 1:1 give the highest yield 60% (Table 1, entry 12).

Read More
193 Words | 1 Pages

Oxidized dextran was reacted with sodium periodate to oxidize. Preparation of Oxidized dextran was done by dissolving dextran (10g) in 100mL of distilled water, then a desired amount of NaIO4. This solution was stirred at a room temperature and shielded from light for 6 hours. The oxidation was terminated by the addition of 2 ml f ethylene glycol. To get the final Odex, the resulting solution was exhaustively dialyzed against water for three days and lyophilized.

Read More
2128 Words | 9 Pages

Lance Feig CH 128L Experiment Report Purpose The purpose of this lab was to synthesize methyl benzoate from benzoic acid and methanol through Fischer esterification. The identity of the product was verified through IR, GC, and 1H-NMR analysis, where the experimental readings were compared to known readings of methyl benzoate. Furthermore, a percent yield of the product was calculated.

Read More
535 Words | 3 Pages

DNA polymerase to build on. DNA polymerase is the most important enzyme that links individual nucleotides together to form the PCR product (Garibyan & Avashia, 2013, p. 1). PCR consists of three steps: denaturation, annealing, and extension. All of the components listed above are mixed together in a test tube and placed in a machine. In the denaturation step, "The reaction solution is heated above the melting point of the two complementary DNA strands of the target DNA, which allows the strands to separate.

Read More
217 Words | 1 Pages

As humans we live for our dreams and aspirations, yet we know so little about their biological purpose and function. The neural basis of dreaming is an enigma that many scientists have pondered over for centuries. From Plato and Aristotle’s theory of consciousness to Sigmund Freud’s hypothesis that dreaming is essentially a safety valve for our unconscious desires, numerous theories have made their way into the medical journals. Today, however, scientists tend to generally support one of these two surprisingly contrasting theories; activation synthesis and threat simulation. Activation Synthesis describes that (insert definition of activation synthesis).

Read More
1888 Words | 8 Pages

CHAPTER 2 LITERATURE REVIEW 1) Orlistat Tetrahydrolipstatin commonly known as orlistat is a lipstatin derivative, produced naturally from Streptomyces toxytricini. It is an effective irreversible inhibitor of gastric and pancreatic lipases (Borgstrom, 1988; Hadvary et al., 1988). 2) Chemical Structure Figure 1: Chemical structure of orlistat (Al-Suwailem et al., 2006) Chemically orlistat is (S)-2-formylamino-4-methyl-pentanoic acid (S)-1-[[(2 S, 3 S)-3-hexyl-4-oxo-2-oxetanyl] methyl]-dodecyl ester. Its empirical formula is C29H53NO5, and its molecular weight is 495.7. (Isidro and Cordido, 2010) 3) Mechanism of action and metabolism of orlistat Orlistat covalently bind on the active site of the pancreatic lipase and a stable complex was formed

Read More
539 Words | 3 Pages

In this laboratory experiment, 3.030 g of Isopentyl Acetate was synthesized and formed by the esterification of acetic acid with Isopentyl Alcohol. 1.0 mL of Sulfuric acid was used as a catalyst in the reaction. The excess Isopentyl Acetate was used to shift the reaction to the right for esterification to occur. During the extraction, the excess of acetic acid and Isopentyl alcohol was extracted with sodium bicarbonate, and further purification of the Isopentyl acetate was done after through drying with anhydrous sodium sulfate and through simple distillation. The percent yield of the Isopentyl Acetate was 46.6 percent with a theoretical yield of 6.502g. In this laboratory experiment the acetic acid was in excess and the Isopentyl Alcohol was the limiting reagent,

Read More
1256 Words | 6 Pages

In western society, an individual’s intelligence is seen as an important and valuable asset in many situations. Since such a high value has been put on an individual’s cognitive ability, it has been speculated whether or not this can be expanded, and, if so, to what extent. In summary, intelligence is a complex trait that is unique to each individual. This can vary among a population despite the similar environments that many people are in, such as a shared classroom or school. There are factors that cannot be controlled, such as genetics and heredity, that also play an important part in determining the intelligence of an individual.

Read More

More about Synthesis Synthesis Preparation

Open Document