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The Leading Cause Of Melanoma

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It can also develop in a single cell when certain genes like BRAF get mutated due to exposure of environmental factors. Which is the most common gene thats related in causing melanoma. When there is damage to the skin from the suns UV rays, or tanning beds it causes mutations in the BRAF gene that can cause the skin cells to uncontrollably multiply and form malignant tumours (Dermnets, 2011). The tumours begin in the melanocytes specialized in making melanin, the pigment carrying skin cells known to give the skin its colour and cause it to tan, by delivering pigment to other cells (Cancer org, 2015). Over exposure to the sun, in particular sunburns are said to be the leading cause of melanoma (Reliant medical group, 2014). Melanoma can start
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Even at a young age, knowing that melanoma is very easy to get may cause the rates of this deadly cancer to drop. This is a cancer that we know how to, and can, prevent. People should be doing everything in their power to do so, for this cancer spreads fast and is most always

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Drug Profile: KEYTRUDA 1. Introduction KEYTRUDA (MK-3475) is a blockbuster immune modulator by Merck for patients with advanced stages of malignancy. The U.S. FDA has assigned MK-3475 a Breakthrough Therapy Designation for Metastatic Melanoma. It is a humanized monoclonal IgG4 antibody against human cell surface receptor PD-1. KEYTRUDA is the 6th approved drug for melanoma and is indicated for patients who have undergone prior treatment with ipilimumab.

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George Washington was on the “front lead” of the American Revolution, and it is no surprise he would become the first president of the United States. He ruled in a blank slated government, since there was no precedents of a government detached from the British. During his mandate The Constitution and the Bill of Rights were created. While the new government was trying to settle, two groups of people were also starting to be distinguished: The Federalists and the Republicans. George Washington’s vice-president, John Adams (who would succeed him) was a Federalist.

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“Warning: That Tan Could Be Hazardous” by Sabrina Tavernise appeared on New York Times, in the January 10, 2015. In her article, Tavernise insists that indoor tanning provides people with skin cancer which might bring them to having melanoma (the most serious type of skin cancer). Sabrina Tavernize says that many factors, including genetics, are at play with skin cancer, one of the largest is the ultraviolet light, which people get during tanning process, it exposures its non burning ray to getting melanoma. Teenage girls from different states, who were intervied said, that tan skin makes them feel “… more confident and more comfortable...,” when they walk around, but they don’t realize what the risk is. According to the information used in the article, tanning beds account approximately 400,000 cases of skin cancer in the United States each year, with 6,000 cases of melanoma.

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She thought that she wouldn't get skin cancer, and she wasn't even that concerned when she noticed a lesion on her skin. It turned out to be a benign form of skin cancer, and she was able to get it removed, but this still didn't stop her from tanning. Unfortunately,

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Symptoms of skin cancer appear in certain places in the body such as redness in certain areas of the skin, other areas away from the natural redness of the skin.(6) Itching affects certain parts of the skin and it is one of the most important symptoms that show periods of intermittent.(6) continuous skin infections are one of the main symptoms of skin cancer, in addition to blue or red spots that appear on the skin.(6) Also symptoms of skin cancer in young people is having protuberances on the skin.(8) Skin cancer can be cured depending on the size of the tumor, its type, depth and location.(7)

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Many are often not diagnosed early enough because they look like moles or other discolorations on the skin. However, Melanoma cancer will have irregular shapes and an oddly shaped border. There may also be wider variations in the colors. This type of cancer is the most dangerous as it does spread quickly to other areas in the body if it is not treated.

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Perceived severity is measured with three items, each having its own 6 point Likert scale. They measured risk for skin cancer based on skin type and natural skin color. The results generally support a model in which intentions are a middle ground between appearance attitudes and tanning behaviors. Reasons to tan and intentions mediate the relationship between sociocultural influenced and tanning behaviors and

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Treatment for melanoma could even include chemotherapy: The treatment of disease by the use of chemical substances, especially the treatment of cancer by cytotoxic and other drugs. Even one indoor tanning session can increase users’ risk of developing melanoma by 20 percent, squamous cell carcinoma by 67 percent and basal cell carcinoma by 29 percent ("A urging issue: indoor Tanning debate heats

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UV radiation is a form of energy from natural and artificial sunlight. Excess amounts can cause damage to DNA in the skin. Although some argue tanning is good for you because it helps form a “base tan” and the UV exposure time is controlled. The truth is, each time you lay in a tanning bed, it increases the risk of developing skin cancer

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In conclusion tanning may be very popular and fashionable, but it poses numerous internal threats and external health threats. With the information about the threats, we need to put a stop to tanning and preserve our natural beauty. External threats such as malignant melanoma and other types of skin cancers, wrinkles, sunburn, and skin aging. These effects are very dangerous on the skin and can be avoided if the effects are known before the damage is already done. The internal health problems ruin the immune system, making it harder to fight skin cancer and other diseases.

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The reason young females have a higher rate of melanoma is because of females indoor tanning. Indoor tanning is potentially dangerous and has been the cause of many deaths. “But my tanning salon says that there is absolutely no possibility of me getting cancer because they use safe tanning rays,” one might complain. Well indoor tanning methods such as beds, booths, and sunlamps are not safe at all, they emit UV radiation rays which is the cause of skin cancer. People need to watch out for indoor tanning as it could lead to a very serious skin cancer.

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On an average day there are about a million people who go tanning on a regular basis, and of those million people, most are younger, between the ages of sixteen and twenty-nine (Hochman). People who use tanning beds before age of thirty-five have a seventy-five percent increased risk of developing melanoma (Fellingham). There are approximately 65,000 new cases nationwide of melanoma and about 9,000 deaths each year from the most preventable disease (Salsberg). Researchers said that there is a death every hour because of melanoma

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The main sign of vitiligo is pigmented or color loss that produces white or light colored patches on the skin. The main parts of the body most at risk for this condition are areas of the skin exposed to the sun. Vitiligo, usually, first appears on the hands, feet, arms, face, or lips because these areas are most exposed to the sun. There are many signs of the condition of vitiligo. The main five signs are skin discoloration, premature whitening or greying of hairs, loss of color in the tissues that line the mouth and nose, loss in color of the inner layer of the eyeball, or discolored patches around the armpit, navel, genitals, and rectum.

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since the skin lost its pigment cells, melanocytes and melanin, vitiligo patients have a higher risk of getting skin cancer. Also, some tanning beds ,which some patients use as a treatmeant, will higher the risk of getting melanoma (a deadly skin cancer). To summarize, protecting the skin from sun light for vitiligo patients is

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