ipl-logo

The Importance Of Corneal Transplantation

928 Words4 Pages

Corneal transplantation is the oldest, most common and most successful transplantation in humans overall. Corneal transplantation refers to surgical replacement of a full-thickness or lamellar portion of the host cornea with that of a donor eye.
General indications of keratoplasty include: optical keratoplasty done to improve vision as in keratoconus, tectonic keratoplasty done to restore or preserve corneal integrity as in descemetocele, therapeutic keratoplasty to remove infected corneal tissue in cases unresponsive to antimicrobial therapy and cosmetic keratoplasty to improve the appearance of the eye which is a rare indication (Seitz et al., 2005).
DONOR TISSUE PREPARATION
Donor tissue should be removed within 12-24 hours of death. The …show more content…

Most hematological malignancies, diseases of the central nervous system such as Creutzfeldt-Jakob disease, Alzheimer's disease, dementia, multiple sclerosis and motor neuron disease are contraindications to ocular tissue donation as well. Other contraindications include recipients of transplanted organs, prior ocular surgery and ocular diseases that are likely to compromise the graft outcome as inflammation and malignancy.
Eye Bank Association of America. Medical Standards. http://www.restoresight.org.
The donor tissue is inspected by slit-lamp biomicroscopy and the endothelial cell count is determined by specular microscopy. A cornea suitable for transplantation should display a noninterrupted epithelial layer, a stroma free of opacities or folds and a viable and regular endothelium with a cell density above 2000-2200 cells/mm2 (Wiffen et al., 1995).
Wiffen SJ, Nelson LR, Ali AF, Bourne WM. Morphologic assessment of corneal endothelium by specular microscopy in evaluation of donor corneas for transplantation. Cornea. 1995; 14(6): 554-561.
O’Day DM. Donor selection. In: Brightbill FS, ed. Corneal surgery, theory, technique and tissue, St Louis: Mosby-Year Book; 1993: 549-562.

Indications for Penetrating and Lamellar Keratoplasty by …show more content…

Impact of graft diameter on corneal power and the regularity of post-keratoplasty astigmatism before and after suture removal. Ophthalmology. 2003; 110: 2162-2167.
PROCEDURE
Excision of donor cornea should always precede that of host cornea. Donor tissue is prepared by trephining a previously excised corneoscleral button. The donor button is usually trephined to be about 0.25 mm larger in diameter than the planned diameter of the host opening to facilitate watertight closure, minimize postoperative flattening and reduce the possibility of postoperative glaucoma. A mechanically-guided trephination is standard although newer non-mechanical laser techniques are more accurate and are preferred by some surgeons when available (Gaster et al., 2012).
Gaster RN, Dumitrascu O, Rabinowitz YS. Penetrating keratoplasty using femtosecond laser-enabled keratoplasty with zig-zag incisions versus a mechanical trephine in patients with keratoconus. Br J Ophthalmol. 2012; 96:

Show More
Related
163 Words | 1 Pages

An organ transplant is an operation that places a healthy organ from one person into another. The organ can come from someone who has died (a deceased donor) and has signed their state’s donor registry or told their family of their wishes to become a donor. Up to 25 different organs can be donated for transplantation. Transplantable organs include the heart, kidneys, liver, lungs, pancreas, and small intestines. According to Donate Life America's 2011 statistics, there were 8,127 deceased organ donors and 6,017 living organ donors in the United States, adding up to 28,535 organ transplants overall.

Read More
555 Words | 3 Pages

An individual who is dissatisfied with the results attained through previous revision procedures, including a surgical rhinoplasty, may choose to have a non-surgical rhinoplasty as a means to address some of these undesirable results. An individual who is not ready to commit to a surgical rhinoplasty, but would like to change certain aspects of his or her nose is an ideal candidate for a non-surgical rhinoplasty with Dr. Tansavatdi. Characteristics That Can Be Addressed With A Non-Surgical Rhinoplasty

Read More
199 Words | 1 Pages

There are many parts of the eye that all play a part in helping us see. The parts we will be examining are the cornea, sclera, optic nerve, iris, lens, pupil, ciliary body, and aqueous humor. Materials: Gloves Cow eye Warm water Paper towel Dissection pan Scalpel Scissors Probe Procedure: Get gloves. Get the cow eye.

Read More
891 Words | 4 Pages

Even if the Torah strictly says that preserving life is a necessity and that transplanting an organ from a dead person is forbidden. The rule is sometimes overturn then an organ such as a kidney could be taken cadaver in other to save another life by transplanting it. Also corneal transplants are approved since its some important for the well-being of the person. Even if saving a life is mandatory in Judaism it is not done if there is a risk for the rescuer. For example, I don’t know how to swim so if I see another person drowning I will not be able to help that person.

Read More
737 Words | 3 Pages

5-Prepare the new generation of transplant physicians and surgeons. In conclusion, Organ donation is a subject of controversy between societies in west and east. In order to implement this program efficiently and avoid the high rates of refusals we need a core cultural development. This development will revolve around changing the mentality of the members of a society while giving them the feeling of social responsibility. Finally since we are living in an islamic society, we have the priority to succeed in this program by following what god says, ”Whosoever saves the life of one person it would be as if he saved the life of all mankind.”

Read More
827 Words | 4 Pages

Eyebrow transplants Eyebrows are one of the more important factors that determine how you look. However, we often underappreciate just how eyebrows define our looks and help express our facial expressions. Only when eyebrows are lost or excessively thinned is their significance really portrayed. A person without eyebrows is guaranteed to attract more attention and startled looks than a person who has lacks hair on the head.

Read More
909 Words | 4 Pages

Group 1: Twenty five eyes for which a deep anterior lamellar keratoplasty was done using double bubble modification of the big bubble technique as described by Foroutan and Dastjerdi (2007). All cases were operated by a single experienced anterior segment surgeon. The recipient operative procedure was done first before stripping the descement membrane from the donor so as not to lose the graft if large DM perforation occurred and the surgeon decided to covert to PKP and it was done as follows: 1- Moxifloxacin HCl ophthalmic solution 0.5% was administrated for one to two days preoperatively, four times daily, to reduce the risk of infection.

Read More
1217 Words | 5 Pages

While the search for matching recipients is under way, the deceased donor's organs are maintained on artificial support. Machines keep blood containing oxygen flowing to the organs. When the transplantation is about to happen, the surgical team removes the organs and tissues from the donor's body in an operating room. First, the organs are recovered and then all the incisions are surgically

Read More
911 Words | 4 Pages

transplants(cite assessing global organ donation

Read More
1311 Words | 6 Pages

Lens Transplants for Cataracts Introduction: Cataracts is a very common eye disease worldwide. Cataracts form when there is a buildup of protein in the lens, and when they are not treated in time, it may lead to blindness. This disease often develops at an old age, as the lens ages, if you have high myopia, long exposure to sunlight, diseases like diabetes or can sometimes be a genetic defect, which means you can get it at birth etc. In Hong Kong, more than 50,000 patients are on waiting lists for cataract operations at Hospital Authority hospitals alone, which the average time for waiting can last up to two to five years.

Read More
872 Words | 4 Pages

CKs consist of pairs of type I (acidic) and type 2 (neutral or basic) CK (Rao, et al., 2014). In response to stress (dryness, shear stress) non-keratinized epithelium can react by keratinizing to form a granular layer and stratum corneum to protect the tissue. This change can be seen in the ocular surface in DED patients (Maumenee, 1979) and in the OME (linea alba) (Canaan & Meehan, 2005; Nanci, 2013)A mucin layer covers and protects the wet epithelial surfaces, such as the ocular surface and the lumen of the gastrointestinal tract, the lungs, and the oral cavity (Argueso & Gipson, 2001; Frenkel & Ribbeck, 2015; Linden, et al., 2008).

Read More
736 Words | 3 Pages

The doctors and nurses involved in a person’s care before death are not involved in the recovery or transplantation of donated corneas, organs or tissues. An individual must also be in a hospital, on a ventilator and pronounced brain dead in order to donate organs. The Gift of Life Donor Program is not notified until life-saving

Read More
1114 Words | 5 Pages

Since the markers on the grafted tissue and those on available tissue are identical (dubbed ‘self’ tissue), the T8 lymphocytes, which are cytotoxic white blood cells that recognize and destroy cells with foreign MHC, will not be triggered and hence they will not attack the grafted tissue (Selitkar, Dikovsky, and Napadensky 797). Previously, organ donations required the use of immunosuppressors which acted on the T8 cells making them tolerate foreign cells with slightly different MHC, but this process weakens the patient’s overall immunity and makes him/her susceptible to diseases (Selitkar, Dikovsky, and Napadensky 797). With the use of bio-printed tissues, this process is rendered unnecessary as the MHC of the transplant is tolerated by the T8 cells of the

Read More
1457 Words | 6 Pages

Other organs which can also be donated are: eyes, ears, nose, nerves, brain, skin, skeleton, gall bladder, stomach, tongue, mouth and muscles. CADAVERIC

Read More
1606 Words | 7 Pages

The list of recipients is six times larger than the list of organ donors (Gonzalez 1). Many organs become unhealthy in the human body, and this causes complications, even death. The most common organs needed for organ transplants are kidneys, hearts, and livers (Guden 6). A person cannot survive without a heart, kidney, or liver, and if any of these organs would start to malfunction, the only hope is that an organ would become

Read More

More about The Importance Of Corneal Transplantation

Related Topics

Open Document