Endpoint Essays

In clinical trials, efficacy and safety are measured by means of certain predetermined endpoints, or outcomes. The main objective of a Phase 3 trial is to demonstrate the efficacy of a drug in the actual target population that is proven in a statistically and clinically significant manner. A Phase 3 trial has a clearly defined primary endpoint(s), pre-specified even before study initiation, because they will determine the power of the study and ensure that the research question is specific. Clinical

Introduction Classroom assessment practices conducted by teachers is one of the integral parts of teaching and learning .Teachers may not know if students are learning or progressing without assessment. Lloyd (2011) explained that these classroom assessment standards comprise a set of criteria and related guidelines accepted by professional organizations as indicative accurate classroom assessment practices. At the heart of assessment system is a clear understanding and connecting to the knowledge

Case Study #1: Technology & Product Review for Endpoint Protection Solutions – Trend Micro Endpoint protection platforms, colloquia referred to as EPPs, initially began as simple anti-virus or anti-malware programs (Solutions Review, 2017). As cyber threats have evolved over the last twenty years, the need for broader information technology security solutions have also grown. Today EPPs have become a “swiss-army knife” security solution. Gartner Inc. an industry leading technology research and advisory

calculations would account for a higher amount of sodium hydroxide solution added. This can be a source of human error, in which it may be difficult to obtain the same color of pink for the different trails. Also, it was fairly easy to go over the endpoint with the addition of a few extra drops of the NaOH solution, causing a dark pink color. A possible improvement to the lab would be to include more trials during Experiment 9 and 10. Performing multiple trials allows for more consistent and precise

The core ideas of calculus, the derivative and the integral, can be developed from natural thinking and curiosity. The derivative is used to calculate the slope of the tangent line at any given point. The derivative was thought of by calculating the rate at which an object was changing at an exact instant in time. The results of the derivative can become more accurate by reducing the difference between the two points in time closer and closer together making them exceptionally close that it may appear

Thus, about 0.002 moles, or 0.4 g, of KHPh is needed. At the endpoint, the number of moles of NaOH equals the number of moles of KHPh used: MNaOH = moles KHPh Eq. 2 VNaOH in liters or MNaOH = g, KHPh x 1000 mL/L Eq. 3 204.23 g/mole mL, NaOH Once the NaOH solution has been standardized, it can be used to determine the

On 1/7, the Alky started to only process FCCU BB and no longer process Coker BB. Alkylation chemistry, neither likes contaminants nor diluents. Contaminants are direct acid consumers. The more contaminants in the feed, the more often the unit will be at an acid constraint. Diluents do not react in alkylation chemistry, but they take up space and decrease the effective area for isobutane and olefin to contact. With less contact, side reactions like polymerization are more likely to occur; polymerization

solution was then titrated with sodium hydroxide until it reached the endpoint. The same amount of acid solution was added to the titrated solution in order for the solution to reach its midpoint. The experiment was repeated. Theories and concepts explored in the experiment include dilution, equilibrium reactions, acid-base indicators, titration, weak acid-strong base reaction, pH, conjugate bases, equivalence point, endpoint, midpoint, dissociation, equilibrium reactions,

John Rawls’ uses his work, A Theory of Justice, to define justice and injustice. Rawls’ general concept of justice follows that all social goods are to be equally distributed unless there can be a situation in which unequal distribution is the the benefit of everyone. The primary social goods he discusses are income, wealth, liberty, opportunity, and the bases of self-respect. Iris Young criticizes Rawls’ conception of justice in her work Justice and the Politics of Difference. Young claims that

be made available and sent to teams that continuously audit endpoint applications. Description New sub-section 5.1.0.2.01 – Application Services Future Statement Unknown services run within UnitedHealth Group workstations will be evaluated using the Information Risk Management risk

Economics 3598: Economics Writing Seminar Keudje Pameni Gaelle Doriane Spring Semester 2018 – Dr. Andrew Hill Paper #1 Assignment Graph 1 depicts a firm operating in a pure or perfect competition market. Pure competition is a market structure with many firms who sell identical products. The firms in that market are price takers and cannot individually change neither the market price nor the conditions of the market. Each firm’s production has perfect substitutes sold by many other firms. Consequently

IT staff and hundreds to thousands of daily alerts, organizations need visibility into every endpoint device, the ability to control access and an automated threat response solution that can bridge the gaps in today’s siloed IT environments.” The panel also discussed designing effective solutions, as

questionequestions patientsd about their feelings and symptoms as well as on documents detailed information regarding their illness by the investigatorcourse of disease. In the ROSETTA-trial theThe main endpoint is of the trial is improvement of QOL QoL and reduction of fatigue. Secondary endpoints are reduction of RT-related side effects such as headache, nausea, and pain. Results: The ROSETTA trial is currently recruiting. Initial results from 30 patients (verum acupuncture n=15; sham acupuncture

Which antacid is the best? Jessica jean-Louis Dario Onfroy Tatyana Preal Avi Horwitz Nicholas Thompson 10/9/15 10/16/15 Abstract: Networks are always advertising the most activate, efficient and long lasting antacid for upset stomach, but which antacid is really the best at neutralizing stomach acid? This experiment looks at which antacid maintains the best neutralization and the amount and duration of time required to maintain neutralization. The reactions between acids and bases of solutions

Edward McClelland is a journalist and the author of several books. In this particular article Mr. McClelland explores the decline of the middle-class. McClelland remembers the 1970’s as an era of blue-collar aristocrats and “The Decade That Taste Forgot” (550). “Although this all began to change in the 80’s” (550). “I know I am dating myself by writing this, but I remember a middle class.” (549) McClelland tells us of a time when a high school dropout could get a job and earn more money than a

dose of medication. A physician followed up with the patients after oral rehydration therapy and a decision to start intravenous therapy was made. The primary endpoint of the study was the proportion of pediatric patients who vomited while receiving oral rehydration therapy among those who received ondansetron or placebo. Secondary endpoints included the number of vomiting episodes during oral rehydration and the rates of intravenous hydration among each group. It was found that the proportion of

The process reaches an endpoint when the two solutions completely and exactly neutralized each other. However, in determining the neutralization time by speculating the change in color, one must be critical and careful enough to get accurate and precise data. In conducting this

interventions. RCT’s have predefined study samples built out of the target population and randomly assigned to different groups (placebo vs. new treatment). The observed effects of investigational treatments at defined time points constitute predefined endpoints. Pharmaceutical companies must meet this standard when working out levels of efficacy and safety that can be achieved by an experimental drug. It is important in a clinical trial to have randomization to prevent the results from being skewed. If

Observing the effects of a catalyst on an enzyme’s rate of reaction Leong, M., Kim, E., Nair, A. Achilly, K., 9/22/2015 Introduction: An enzyme is a protein that acts as a biological catalyst. A catalyst increases the rate of reaction by reducing the activation energy required (Reece 2005). Catalase, an enzyme produced by most living organisms, catalyzes the decomposition of H2O2 in our bodies in order to maintain homeostasis. Enzyme activity involves the binding of an enzyme to a substrate

balanced chemical equation for this titration? NaOH + HCl → NaCl + H2O 4) Define: Standard Solution: Titration: A lab procedure used to determine the concentration of a solution by neutralizing it with a solution of another known concentration. Endpoint: pH at which indicator changes color and titrating is stopped. Volumetric Analysis: A measurement of volume of a solution of a known concentration which is used to determine the analyte’s concentration. Gravimetric Analysis: A technique to determine