Adverse Drug Reactions Case Study

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Adverse drug reactions (ADRs) have been reported with significant impact on morbidity mortality, quality of life and health care cost. It has been estimated that approximately 2.9-5.6% of all hospital admissions are caused by ADRs and as many as 35% of hospitalized patients experience an ADR during their hospital stay.[1-3] In an Australian study 5.7% of all admissions were drug related, out of which 4.9% were due to ADRs and it calculated a cost of more than € 2million per patient.[1] A study conducted in Germany estimated that direct cost associated with ADRs were 0.4 billion dollars annually.[2] United States study[3] revealed that the cost of ADRs per patient was in the range of US $2000 to US $4000. In India, Ramesh et al estimated cost associated in treating all reported ADRs was US $1595, with average US $15 per ADR.[4]