Botox Research Paper

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The use of neurotoxin “periodic botulinum toxin” injections is considered to be the gold standard treatment for adductor spasmodic dysphonia. Botulinum toxin is produced by the bacterium clostridium botulinum and attains a “reversible neuromuscular blockade at presynaptic terminals, therefore, preventing the release of acetylcholine in response to action potentials” (Holden, Vokes, Taylor, Till & Crumley, 2007). Botox is directly put into the affected muscles of the larynx; therefore, injection of Botox is done in the thyroarytenoid or lateral cricoarytenoid muscles in individuals with adductor spasmodic dysphonia (Woo, 2009). Botox helps weaken the muscles by blocking the nerve impulse to the muscle and therefore improving the voice (Turkington

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