Nigel Courtenay-Luck, Ph.D., CSO of Antisoma, at a recent 9th European Biotech Crossroads meeting, talked about data from Phase 1 of a study on a new type of biomolecule called an aptamer. He said that aptamers are very similar to antibodies; they can both recognize and bind to antigens, they both have low nanomolar binding, and the pKa of both molecules can be modified easily. He said that they are ideal to be used as therapeutics because they can bind well(since they are 3-D) without causing an
The use of neurotoxin “periodic botulinum toxin” injections is considered to be the gold standard treatment for adductor spasmodic dysphonia. Botulinum toxin is produced by the bacterium clostridium botulinum and attains a “reversible neuromuscular blockade at presynaptic terminals, therefore, preventing the release of acetylcholine in response to action potentials” (Holden, Vokes, Taylor, Till & Crumley, 2007). Botox is directly put into the affected muscles of the larynx; therefore, injection of
25BHS suggests to read tAfï[]me (“from doing”) with 1QIsaa and LXX. Whether we follow BHS proposal or the MT reading, the meaning of the line remains the same since in poetic parallelism the preposition !mi in v. 13a (tB'V;m)i governs the following line (v. 13b). However, the BHS proposal is a more a plausible reading because of tAfï[]me in v. 13e. 261QIsab, Theodotion, Syriac, Targum, and Vulgate read ^yc,Þp'x] (pl.) as ^c.p.x, (sg.). We opt for ^c.p.x, because of the recurrence of the term in v
which is toxins. The scientific name is known as Paralytic Shellfish Poisoning or (PSP). Starting off, paralytic shellfish poisoning is a silent killer. Paralytic poisoning is an illness caused from eating shellfish that have been exposed to dinoflagellate algae ("Paralytic Shellfish" 2 . This is a natural occurring toxin, that is caused by some types of microscopic algae. This toxin affects the nervous system and can even cause damage to the muscle system. In other cases, when the toxin level is
Year 9 Science Ecology Symbiosis Symbiosis Symbiosis is the relationship between two living organisms. The main types of symbiosis are mutualism, parasitism and commensalism. The association between the two organisms can be beneficial to one or two of the species or in some cases be harmful, depending on the type of symbiosis. Commensalism Commensalism is a biological term which is used to describe the relationship between two living organism, where in which one benefits from the other without
death to the exposed individual. The basic mechanism of the toxin (which has eight serotypes) is blocking the release of a neurotransmitter Acetylcholine (ACh) at the synapse between the motor neuron and a muscle (1). By obstructing the release of ACh at the neuromuscular junction, the muscle is unable to contract thus, causing muscle paralysis. This potent toxin has therapeutic as well as cosmetologic uses. I will focus on how C. botulinum toxin is used in surgical cosmetology as well as describe how
Assalamualaikum and a very good morning I bid to my lecturer, Madam Rosyati, and my fellow classmates. My name is Aina Izzati Binti Mohd Khair, S37085 and I am from K1. Nowadays, the earth is facing global challenges such as climate change and pollution which occurs due to human activities. As some of us know, plastic bag is one of the contributors for waste pollution. This is why I strongly believe that the usage of reusable bags should be enforced in our country, Malaysia as the use of plastic
For pool owners, there is nothing more exhausting than cleaning the pool itself. Perhaps the common denominator as to why people want to own a pool is that they want to relax and enjoy it with their family and friends. That is the reason why most pool owners prefer to buy robotic pool cleaners. Having fun in the water is only the peak of an iceberg of having a pool. The rest of the iceberg lies on pool maintenance. It would probably take more time cleaning the entire pool than the actual leisure
You can make it happen with a single Botox injection. The results from this cosmetic procedure have made it a Hollywood craze and it has now become much more accessible to non-celebrity patients as well. What exactly is Botox? Botox is botulinum toxin for short. It is a substance that is derived from Clostridium botulinum, a kind of bacteria that may cause food poisoning that can be fatal. It does sound scary. However, in controlled amounts, it can do wonders for wrinkles. What is used in Botox
Germ theory of disease is one of the theories in the biology field. Germ theory of disease supports that microorganisms that are germs are the cause of diseases. This theory was first proposed by Girolamo Fracastoro in the 16th century but he was not able to provide any evidence to strengthen his proposal. This theory was not accepted easily by the citizen between the 16th century to the 18th century. The pre-existence of miasma theory was the obstacle to the acceptance of germ theory during that
Chapter nine commences by telling its readers about how Lee Harding was diagnosed with E coli 0157:H7. After eating some tacos at a Mexican restaurant, he started to have excruciating stomach pains and diarrhea. Harding’s stomach was hurting because of some frozen hamburgers he ate a couple of days ago. Those same hamburgers provided by Hudson Foods were infected with E. coli 0157:H7. Millions of those same frozen hamburgers had already been sold and most likely eaten. The middle of the chapter
that more than half of the cases of laminitis are induced by an excesses of carbohydrates in the animal’s diet (Millinovich). Large structural carbohydrates in the form of sugar, fructans, or starch are indigestible to mammals without the help of microbial hindgut fermentation (Pollitt, Visser). When a horse ingests too many grains, the primary microorganism that is responsible for “the rapid fermentation of carbohydrate to lactic acid in the equine hindgut is called S. bovis” (Pollitt). “Most of the
Introduction: The Urinary Tract Infections are one of the most important microbial infectious diseases which may cost millions of dollars every year for different countries and governments. Among diverse microbial Urinary Tract Infections, those which are caused by Uropathogenic Escherichia coli involve a high frequency of diseases around the world. For this reason, the authors are going to discuss about the different aspects of UPEC pathogenicity and the urinary tract infections caused by E.coli
and are functionally not influenced by varying stomach environment. In fact, a synergistic digesting effect is produced by a combination of these two enzymes. Activated charcoal is totally inert and is incorporated in Unienzyme to adsorb gases and toxins to offer relief from abdominal distension and dyspepsia. Thus, it serves to complement the role of
you have discovered the right article in the event that you searching for a urinary tract infection (U.T.I) treatment utilizing no anti-microbial. Body: In the event that you have been watching the news lately, you most likely have seen that numerous anti-microbial are getting unfavorable criticism. Much of the time (like urinary infections), anti-microbial are accomplishing more mischief than great. Case in point, more than 25% of anti-infection clients will redevelop another infection inside
Mastitis (infectious) Overview: Mastitis is a very common disease among women who have just given birth (that is called puerperal mastitis) and is quite annoying and painful as it is a real infection that affects the breast tissue that is very swollen, hot and flushed. Causes: When mastitis makes its debut one feels a strong burning during lactation and in general it feels very exhausted and tired. Puerperal mastitis is caused by a blockage of breast milk (which is formed when a breast is not
responses as a result of all kinds of stress experienced by the individual. Moreover, add to physical and psychological stresses deficient or excessive eating, lack of proper nutrients, lack of good vitamins and minerals, or an excess of calories, toxins and other molecules that are not normally found in nature, and you just worsen the overall toxicity condition. The cellular environment and chemical stress on the cells will be more harmful. Any inconvenient lifestyle (junk food, sedentary lifestyle
article “Protecting Ourselves from Food: Spices and morning sickness may shield us from toxins and microorganisms in the diet”, Sherman and Flaxman argue that “Microbiologists and food scientists have challenged various food-borne bacteria and fungi with spice chemicals. Although the data are heterogeneous—owing to differences in laboratory techniques, phytochemical concentrations and definitions of microbial inhibition—there is, nonetheless, overwhelming evidence that most spices have antimicrobial
by easy only be seen with a microscope. The bacteria that cause disease are called pathogenic bacteria. Bacterial diseases happen when pathogenic bacteria inter the body and begin to reproduce and grow in tissues. Pathogenic bacteria may also emit toxins that damage the body. Common pathogenic bacteria and the types of bacterial diseases they cause include: Salmonella and Escherichia coli cause poisoning food . Staphylococcus aureus a different infections in the body canhappened, for example: boils
Clostridium difficile Clostridium difficile is a microbial bacterium that is also human pathogenic. C. difficile is usually found in a hospital environment, and in the form of endospores. Due to bad hygiene, it can be transferred from things like a bedpan or unsanitary surface into the body orally. It goes through the mouth and ends up in the intestines where it comes out of the endospore state and into its vegetative state. While in the intestine C. difficile starts to flourish and that is when