ipl-logo

The Mouse Body

845 Words4 Pages

Nowadays thanks to the transgenic techniques, the mouse has become the major animal model used for studying congenital cardiac anomalies and DNA defects induced by chemical substances.(34)
C57BL/6 is the most widely used strain produced by a minimum of twenty generations of brother-sister mating.(35) Its genome has been sequenced and they are known as good breeders.(36) Regarding the anatomy of the mouse heart, the thymus gland is well developed and presented anterior to the heart.(37) The heart is surrounded by pericardial membrane which consists of visceral and parietal portions.(37)
The heart is formed of two ventricles and two atria.(37) Each ventricle is cone shaped, with thick wall, pointed apex and broad base.(37) The two ventricles …show more content…

The atria are small, thin walled chamber presents anterior to the base of each ventricle.(37) Unlike the human heart where four pulmonary veins open into the left atrium to drain oxygenated blood from the lungs, in the mouse heart, the pulmonary veins form a pulmonary confluence and open into the left atrium by a solitary …show more content…

Another difference between the two species that in the mouse heart, the left superior caval vein persist and deliver blood from the back of the head.(37) The left superior vena cava joins the right superior vena cava and drain with the inferior vena cava into the right atrium.(37)
Each of the right and left superior vena cava have five vessels draining into it, the internal thoracic, azygos, subclavian, internal jugular, and external jugular veins.(37) The inferior vena cava is a single vessel originates at the caudal end of the abdominal cavity and terminates with the right superior vena cava into the right atrium.(37) Hepatic, renal, right gonadal, iliolumber and common iliac veins drain into the inferior vena cava.(37)
The conduction system in the mouse heart is also different from that of a man heart.(37) In the mouse heart, the sinoatrial node is located above the junction between the left and right superior vena cava rather than the atrium itself as in the man heart.(37)
The AV node and the bundle of His in the mouse heart is similar to that present in the man heart, while the Purkinje fibers are less developed suggesting that the impulse conduction system pass directly within the

Show More
Related

Unit V Cardiovascular System

760 Words | 4 Pages

Unit V- Cardiovascular system Subheading: 1. Cyanotic Congenital Heart Diseases 2. Acyanotic Congenital Heart Diseases 3. Acute Rheumatic Fever 4. Rheumatic Heart Disease 5.

Read More

Neovison Dissection Lab Report

1640 Words | 7 Pages

Next, they traced the external jugular vein and its tributary veins on the surface of the right side of the neck and head. On the left side where the sternomastoid was cut, the students then located the deeper vessels running alongside the trachea, internal jugular vein, and the common carotid artery. In the abdominal cavity, the groups then exposed and studied the hepatic portal vein and its tributaries. They then identified the tributaries of the post cava, the renal, adrenolumbar, iliolumbar, iliac, and caudal vessels. The arteries of the gonads then came off the abdominal aorta cranial where the spermatic arteries were found.

Read More

Summary: Skeletal Muscles

1789 Words | 8 Pages

Electrical signals begin at the SA node, bringing about atria contraction, and after that proceed onward to AV node, postponing electrical impulses to permit blood from the atrium to fill the ventricles. Signals move from the AV node to the heap of His and after that to the Prukinje fibers, which then permit the ventricles to contract. A heartbeat includes a contraction stage systole and an unwinding stage diastole. These contractions of the heart are animated by electrical impulses which begin from the nodes that are available in the heart; sino-atrial (SA node) and the atrioventricular (AV node). These nodes are bunches of nerve of

Read More

Annex 1 Heart Murmur

951 Words | 4 Pages

Cardiac murmurs can be present at birth (congenital; often caused by malformations) or acquired and manifests later in the animals life. (Ex: disease of the cardiac muscles, disease of the cardiac valves, etc.). It is important to note that many animals with heart murmurs can live a long and happy life without

Read More

Jane Doe Case Summary

853 Words | 4 Pages

The left atrium was slightly enlarged measuring 4.2cm and the IVSD measuring at 1.5cm. In the short axis, planimetry was preformed but did not receive an accurate valve area. M-mode through the aortic valve showed only 1.1cm of separation of the right and non-coronary cusps during systole. While in apicals, I was able to obtain a max pressure gradient of 34mmHg, peak velocity of 3.1m/sec and an aortic valve area of 1.5.

Read More

Zebrafish Heart Regeneration Lab Report

1599 Words | 7 Pages

The TEM showed the cardiac muscle structure in the untouched hearts in a Z-shape (a, b), while the regenerating heart cell arrangement began disconnecting and created lots of space between the cells (c, d). The myosin seen in the normal heart turns out to be disorganized (f), and after 7 days the space was once again present (e, f). Around the 7th day, the distortion of the cell structure increased, resembling those with BrdU. However, TUNEL proved that the cardiomyocytes appeared normal and showed no signs of apoptosis. Cells with the PH3 marker showed no signs of noticeable sarcomeric organization, while PCNA-positive cells showed the

Read More

Bundle Branch Block

747 Words | 3 Pages

A bundle branch block anatomy involves the heart, but specifically the electrical nodes of the heart and the chambers of the heart. The electrical nodes of the body act as a pacemaker to help the heart correctly beat. The sinoatrial node (SA node) will send impulses to help the heart to contract. This impulse is sent to the upper chamber of the heart and then passes through the atrioventricular node (AV node). This impulse is sent through a pathway

Read More

William Harvey's On The Motion On The Heart And Blood In Animals

713 Words | 3 Pages

Vesalius had observed, by dissection, that there were no pores in the septum of the heart. This meant that direct transfer of blood was not possible. Harvey’s explanation for how blood was transferred from the right ventricle to the left ventricle was that it went through the lungs via the pulmonary arteries and returned through veins to the left auricle, and subsequently to the left ventricle. Once again this description was a simplified explanation of flow in line with his observations and those of Vesalius and

Read More

Analysis Of Paul Cardall's Before My Heart Stops

637 Words | 3 Pages

Ventricle heart defect may consist of a single ventricle or as for Cardall a double-inlet ventricle defect. A single ventricle heart defect is the most common and the left ventricle heart defect is affects the right ventricular anatomy (Porth & Matfin, 2009). With the tricuspid valve not opening and closing properly is a common cause for the left ventricle defect (Porth & Matfin, 2009). The DILV defect is where the left ventricle has two inlets, the pulmonary and systemic venous return mixes, and finally puts pressures on the right ventricle (Porth & Matfin. 2009). Cardall (2010) defined his DILV as the left and right atria empting into the same

Read More

Explain The Function Of The Pulmonary Artery

515 Words | 3 Pages

Similarly to the pulmonary artery, the pulmonary vein has very thin walls although the vein’s walls are even thinner than those of the pulmonary artery due to the wider lumen and low pressure of the blood. The pulmonary vein also contains little elastic fibres as the shape of the veins do not need to be maintained as rigidly as those of the artery due additionally to the low blood

Read More

Mouse Of The Mouse And The Moose Summary

727 Words | 3 Pages

My Product is a children's book that is called “A Tale of Mercy and Justice: A Story of the Mouse and the Moose”, that tells the story of a mouse and a moose who become friends and work together to help a group of animals in need. The story follows the mouse and the moose as they come to the realization that justice and mercy must go hand-in-hand to provide a better life for those in need. The book is illustrated with vibrant and colorful artwork that captures the beauty of the forest and its inhabitants. The book is written in a way that even young readers can understand and relate to the characters and their struggles. At the end of the book, there is a moral lesson about justice and mercy, and how everyone can make a difference by working

Read More

The Mouse Essay

890 Words | 4 Pages

In the satirical short story, “The Mouse” by Saki, Theodoric Voler can be analyzed through a socioeconomic lens, as it explores the concept of class and power. Theodoric is a sheltered man who is out of touch with the world outside his limited experiences. His lack of skills and knowledge can be attributed to his privileged upbringing, which has shielded him from deeper human connection and forced him to rely on others for his needs. According to Standford University, “classism is the institutional, cultural, and individual set of practices and beliefs that assign differential value to people according to their socioeconomic class”. One of the main ways in which classism is a result of socioeconomics is through the creation of social hierarchies.

Read More

The King Of Mice Analysis

187 Words | 1 Pages

In a little abandoned village there were some vacant homes where lives a lot mice, despite the houses were all shattered. The mice founded this place very comfortable,and they grew in numbers timely. Along the border of abandoned village there was a lake.

Read More

Congenital Heart Disease

2144 Words | 9 Pages

“A VSD is the most common type of heart malformation present at birth” (10). It is estimated that the majority of congenital defects can be explained on the basis of simple dominant or recessive inheritance, while 10 percent of them can be attribute to viral infections, intrinsic factors and or major chromosomal abnormalities (14). It has been shown that chromosomal abnormalities such as down syndrome can be attributed to the onset of a ventricular septal defect in an individual. Septal defects are the result of abnormal development of the interatrial septum.

Read More

The Circulatory System In The Human Body

1538 Words | 7 Pages

According to Ballard, "Inside the heart there are four spaces called chambers. A thick wall, the septum, separates the two sides the heart. Each side has an upper chamber (atrium) and a lower chamber (ventricle)" (6). Blood flows into the heart from the atria, and leaves from the ventricles, creating the heartbeat

Read More

More about The Mouse Body

Related Topics

Open Document