Nevus lipomatosus superficialis is an uncommon beningn hamartomatous skin lesion. The classic type of NLCS is usually unilateral as seen in our case. The classic variety of NLCS is either present at birth or can arise at any other time within in Ist two decades of life4,5,6. There are sporadic case reports of coexistent anomalies in the form of café-au-lait macules and scattered leucoderma. Increased hairness and comedo-like lesions have also been reported7. The histopathology of NLCS usually shows a normal or slightly attenuated epidermis associated with dermal proliferation of mature adipocytes in the reticular dermis that may extend to papillary dermis . The adipocytes most commonly form small aggregates around blood vessels or eccrine glands, but may also be present as solitary adipocytes between collagen bundles. …show more content…
The adipocytes may show conection to the underlying subcutaneous fat or be separated from the subcutis by collagen .Less commonly ,spindle cells representing immature fat cells may also be present. NLCS should be differentiated from nevus sebaceous, skintags, neurofibroma, lymphangioma and focal dermal hypoplasia (Goltz syndrome). Histopathological examination usually helps in the differentiation. No fat cells are present in the dermis in the case of skin tags. Simillar dermal collections of adipocytes on histopathological examination are also present in some melanocytic nevi,pedunculated lipofibromas and in Goltz syndrome. Lipofibromas contain fat cells, but no skin appendages in the dermis. In the case of Goltz syndrome, there is absence of collagen in the atrophic dermis and skin appendages are absent. The precise etiopathogenesis of NLCS is not