Differences Between the Colonies The three Northern and Southern Colonies on the eastern side of early America, have their similarities, but that still doesn’t compare to their vast differences .When contrasted, the topic can go from religion, to climate, and even to the very accent or language that they may speak. Then in return, giving each colony their own “distinct” qualities to be represented for. The first thing that differs between the Northern, Southern, and Middle colonies, is their climate, and what they grow for food and trade. In the North Colonies’ climate is bitterly mild which means long cold winters and mild short summers.This helps the Northern people grow crops like corn, pumpkins, beans, squash, oats, etc. Whereas with the