Infants born before 37 weeks are considered premature. There are many influences of premature birth. However, the cause of premature birth is not always known, but common cause are external threats to maternal and fetal health including the mother’s use of drugs, alcohol consumption, cigarette smoking, poor nutrition and low weight gain. Also its physical stress, and lack of prenatal health care. For example, some mothers may not be aware during the first trimester. This can cause the mother to not have the proper care during the most critical time of their pregnancy, which is the first stage of the infant’s development. Medical conditions that can cause premature birth include illness such as high blood pressure and diabetes, etc. Premature