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Endocrinology Summary

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HISTORY OF ENDOCRINOLOGY *Study of endocrine glands is known as endocrinology. *Thomas Addison is known as the Father of endocrinology. *Aristotle (384 – 322 B.C.) described with great accuracy the effect of castration in men and birds. *Around 1690 Ruysch described that organs such as thyroid that produced important substances which entered the blood stream. *Thomas Wharton (1614-1673), noted the distinction between ductile and ductless …show more content…

It travels through the body in the blood and exerts its effect on a particular target tissue. *Edward Kendall (1914) purified the hormone thyroxine from the pig thyroid. In 1921, thyroxine was synthesized. * In1916 P.E. Smith and Bennet Allen, separately pointed out that pituitary surgery resulted in a diminished growth rate and reduced degree of function of the thyroid gland. *Fredrick Bunting and Charles Best (1921) extracted insulin from the pancreas of fetal pigs to produce the first preparation to treat humans suffering from diabetes mellitus. *Otto Lowei (1921) first identified neurohormones. *Collip (1925) discovered and purified

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