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Zoonotic Influenza Virus

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The purpose of the article is to assess the need to update CVV for preparedness against pandemics caused by zoonotic influenza viruses. The article thus describes the genetic and antigenic characteristics of these viruses. Influenza A viruses are categorized by two proteins they carry on their surface; their HA (hemagglutinin) and NA (neuraminidase), resulting in subtypes like four viruses mentioned in the article viz. Influenza A(H5), Influenza A(H7N9), Influenza A(H9N2), Influenza A(H3N2) variant (v)^5. Many of the combinations are yet to be observed in nature. Within each strain, there are many genetic groups called clades, and within each clade exists subclades and within each of these, many variants may exist. And over time these clades,

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