AD-process is a remarkably selective one in that it develops in only a minority of neuronal types while sparing all of the rest. Clinical symptoms develop subtly, and nerve cell impairment leads to a gradual loss of fundamental functions that first appear after a given threshold is exceeded (Figure 1)(Braak and Del Tredici, 2015). Morphologically speaking, some neural cells are more vulnerable than the others (Figure 5) i.e. projecting neurons with an axon that is disproportionately long in relation to the size of cell soma(Braak and Del Tredici, 2015). Most prominent loss of neurons which were first gained attention were cholinergic neurons followed by a loss of cholinergic transmission resulting in learning and memory dysfunctioning(Kar et