Acute Renal Failure Acute renal failure (ARF) can be attributed to trauma, obstruction, poor circulation or kidney disease. At this stage, it is reversible if caught early, otherwise, if untreated, will lead to chronic renal failure. If trauma is involved, hypovolemia should be suspected and the subheading should be pre-renal failure. The pathophysiology for pre-renal failure is due to conditions that damage blood flow to the kidneys and when there is a disruption to renal blood flow, oxygen is interrupted too. This in turn, creates hypoxemia and ischemia which eventually destroys the kidney(s) and cause permanent damage. Also, due to the hypoxemia, the tubules are most disposed to the effects of hypoxemia. If inflammation comes into play, the delicate layer beneath the epithelium will become permanently damaged, leading to chronic renal failure. Due to the severity or delayed blood flow due to ischemia, can lead to renal damage and cause an excess of nitrogen in the blood. …show more content…
The pathophysiology is when the nephron has progressed to the point of nonfunctionality at about 75%. At this point, toxins will have built up within the body and all major body organs will be affected. The patient will be on some type of conservative diet, medications and dialysis as well. Eventually, due to the destruction of said organs, his immune system will weaken and death will ensue. At some point, the patient and family will need to be referred for appropriate counseling and