Cystic Tsui: A Genetic Disease

Introduction:

According to Learn.Gentics (2015) ' A genetic disorder is a disease that is caused by an abnormality in an individual 's DNA '. These abnormalities can be found in a variety of different ways. They can be as minute as a change in a single base-pair inside a gene to the addition or subtraction of a whole Chromosome. No matter how big or small the abnormality is, they can cause numerous amounts of genetic diseases which can change a persons life forever. Genetic diseases are passed down from a carrier parent to their offspring. Depending on what type of genetic disease it is, depends on how many parents it takes to pass the disease on to their offspring. In some cases it 's one parent and in other cases its both parents. Some

Lap-Chee Tsui. The team were based in Toronto, Canada at the Hospital for Sick Children. Dr Tsui was later on inducted into the Canadian Medical Hall of Fame in 2012 for his remarkable breakthroughs in human genetics. Cystic Fibrosis is one of many genetic disease and affects around one in 2500 Caucasians. It is also said that one in 25 people in Australia are carriers of the disease. The disease is mostly common in Caucasians and other white ethnicities and much more uncommon in Asian and African ethnic groups. Cystic Fibrosis is an autosomal recessive disease which basically means the disease is found equally in both females and males. CF can only be passed down from parent to

than other treatments as, gene therapy disputes with root cause of the disease instead of disputing with the symptoms of the disease. The concept of gene therapy is to replace the abnormal gene with a correct gene (see appendix four). As technology has improved so has gene therapy. There are now two different types of treatment available to sufferers; Germ Line and Somatic Gene Therapy. The most effective of the two is the Germ Line treatment as it not only helps the individual with CF but their offspring as well. It

helps correct the default in the DNA sequence for future generations. Where 's Somatic only corrects the abnormality in the sufferer who could still pass on the disease to their children. Looking at how much technology and research is improving, treatment for cystic fibrosis is also improving making it easier for sufferers and allowing them to live a longer life.

Conclusion:

Cystic Fibrosis is the most common autosomal recessive genetic disease affecting one in 2500 Caucasians. People affected by the disease don 't have a long life expectancy and suffer great breathing and digestive difficulties due to the mucus build up in their lungs, airways and digestive system. However with the vast improvement of technology scientists and researching are coming up with better ways for treating Cystic Fibrosis, like gene therapy which will hopefully one day make Cystic