Lockjaw, also more commonly know as tetanus or Clostridium tetani, is a desease caused by bacterial infection. the bacterium Clostridium tetani, is commonly found in soil, saliva, dust, and manure and can be introduced to the blood stream via a skin puncture, the bacterium produces a toxin called Tetanospasmin which interferes with muscle contractions, resulting in muscle spasms or spasmodic muscle contractions. (https://en.wikipedia.org/wiki/Tetanus). Tetanospasmin permanently binds receptors, so in that sense it can 't be cured. In the case of advanced tetanus treatment involves antibiotics and paralytics while being put on a respirator, which is needed until your receptors regenerate.(Andrew Lehman, Immunologist and Virologist, https://www.quora.com/How-can-tetanus-be-cured).
Tetanus often begins with mild spasms in the jaw muscles—also known as lockjaw or trismus. The spasms can also affect the
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Chest, neck, back, abdominal muscles, and buttocks may be affected. Back muscle spasms often cause arching, called opisthotonos. Sometimes the spasms affect muscles that help with breathing, which can lead to breathing problems. An endospore is a non-metabolizing survival structure that begins to metabolize and cause infection once in an adequate environment. Because C. tetani is an anaerobic bacterium, it and its endospores thrive in environments that lack oxygen. Hence, stepping on a nail (rusty or not) may result in a tetanus infection, as the low-oxygen (anaerobic) environment is caused by the oxidization of the same object that causes a puncture wound, delivering endospores to a suitable environment for growth. exclusively in persons unvaccinated or