Abstract: In this experiment, triphenylmethanol was synthesized in two steps. First, the bromobenzene was reacted with dry magnesium turnings to produce Grignard reagent. Second, the Grignard reagent was reacted with methyl benzoate and concentrated sulfuric acid to produce an alcohol. The end result of the experiment was not very successful because only 17% yield of final product triphenylmethanol was recovered, and the final product was impure based on the melting point and the IR spectrum results.
Lab Report 5: Acetylsalicylic Acid (Aspirin) Synthesis Name: Divya Mehta Student #: 139006548 Date Conducted: November 19th 2014 Date Submitted: November 26th 2014 Partner’s Name: Kirsten Matthews Lab Section: Wednesday 2:30 L9 IAs Name: Brittany Doerr Procedure: For the procedure, see lab manual (CH110 Lab Manual, Fall 2014) pages 96-98. Wilfrid Laurier University Chemistry Department. Fall 2014. Acetylsalicylic Acid (Aspirin) Synthesis.
The goal of experiment four was to use sodium dichromate to oxidize borneol to camphor. To purify the camphor use sublimation, then reduce camphor to isomeric alcohol isoborneol with sodium borohydride. Use the 1H NMR to determine the ratio of borneol to isoborneol in the final product. The experiment was carried out by using sodium dichromate to oxidize a borneol solution that was made with borneol and ethyl acetate. Once the reaction was complete the mixture was transferred into a separatory funnel where the ether and aqueous layers were separated and the aqueous layer was then extracted with two portions of ether.
Abstract During this experiment we will produce Isopentyl Acetate via the fisher mechanisms. The alcohol group is converted into an ester giving off a banana scent. This reaction does not favor the products therefore we must add an excessive amoinut of Acetic Acid to shift the equilibrium to favor the products. Our results showed a successful reaction by comparing our boiling results and infrared results to the textbook data on Isopentyl Acetate. Introduction Isopentyl Acetate is an ester that is commonly referred to as banana oil, this is due to the similarity in odor of bananas.
Eudiometer Experiments in Elemental Effervescent Expansions Joe Williamson and Ethan Kang Mar 13, 2023 Purpose: The purpose of the gas laws lab was to calculate the volume of gas produced from a specific mass of magnesium ribbon. It also aims to use gas laws to determine the theoretical yield and volume of hydrogen gas produced at STP. Procedure: Gather Mg ribbon, string, a 2000-mL beaker, a Eudiometer, a 100-mL beaker, 50-60 mL distilled water, and HCl.
Extensive studies revealed that eucalyptol is considered to be a chemical which is safe when taken in normal doses. In higher doses, eucalyptol is hazardous via ingestion, skin contact or inhalation. Eucalyptol doesn’t show genotoxicity or carcinogenicity, but the substance may be toxic to the reproductive system. Repeated or prolonged exposure to the substance can produce damage to target organs 59.
After inhalation, 59%-62% is eliminated in the urine and 32%-34% in faeces. About 8%-13% is excreted unmetabolised in the urine, and about 15% to 18% is excreted in the urine as conjugates. The terminal half-life after inhalation is estimated to be 17 hours. 7.0 Contraindications/Adverse Side Effects 7.1 Contraindications for Formoterol include hypersensitivity to Formoterol or to Lactose Monohydrate; may cause anaphylaxis, severe hypotension and angioedema.
The objectives of the experiment is to assess the changes in action after a single oral intake of toluene, white rats are used to determine the motor impairments brought by the said chemical using the Functional Observation Battery (FOB) Test. The last objective is to observe if ingestion of toluene has any morphological and anatomical effect on different organs. The significance of using the oral dose of toluene in rats is that it will be subjected to the rat’s metabolism and depending upon the drug, a part of it will be degraded by the body’s metabolic processes. This shows that only a part of the drug administered reaches the blood and this is called bioavailability.
Intrinsic clearance of haloperidol is due to glucoronidation by uridine diphosphoglucose glucuronosyltransferase, oxidation by cytochrome P450 and reduction by carbonyl reductase. The elimination half-life for haloperidol is 12-38 hours. Complete elimination of an oral dose of haloperidol takes 4 weeks. Five days after the administration of haloperidol, approximately 40% of the dose of haloperidol will be excreted in urine and 15% will be excreted in the faeces.
Designing a Therapeutic Dosing Regimen for a Novel Potential Treatment of Alzheimer’s Disease Allopregnanolone is a metabolite of progesterone and a naturally occurring steroid hormone, which acts as a positive allosteric modulator on the GABAA receptor, producing anaesthetic, anxiolytic and sedative effects. The notable exception to this appears to be in the brains of adolescents, where it acts as a GABAA antagonist, causing mood swings. (National Center for Biotechnology Information, n.d.) It is found to be secreted in the urine of pregnant women (National Center for Biotechnology Information, n.d.), and levels have been found to naturally fluctuate during pregnancy, the menstrual cycle (Luisi S, 2000), and stress (Girdler SS, 2001).
When using this, it has been known to cause iridoid glucosides by human fecal flora transformation (site). Specifically for pharmacodynamics, the goal is to observe drug absorption, distribution, and
The basic principle for the synthesis of kestoses involves the action of invertase on sucrose. Invertase hydrolyses sucrose, producing glucose and fructose. Invertase also plays a very important role in kestose synthesis: It transfers the fructosyl residue (resulting from hydrolysis of sucrose) onto the fructose residue of sucrose (1- and 6- kestose) or the glucose residue of sucrose (neo-kestose). In this way, the respective kestoses (1, 6 and neo) are created. The method used for the synthesis of the kestoses was adapted from Gross (1962).
To purify and isolate trimyristin from a nutmeg, the sample of nutmeg was mixed and refluxed with dichloromethane before isolating and purifying the trimyristin through vacuum filtration and recrystallization. After refluxing the solution of dichloromethane and nutmeg, an intense amber colored solution was recovered. Through the process of vacuum filtration and recrystallization, a white, powdery and clumpy sample of solid trimyristin was collected. Of the 8.004 grams of nutmeg utilized in the experiment, 2.399 grams of trimyristin was collected after recrystallization, resulting in a 29.97% recovery in the experiment. By conducting a melting point experiment, the melting point for our extract of trimyristin was most accurately determined to be 50.3℃ - 51.6℃.
Before calling the poison control center or emergency health care professional, try to determine the following information, Patient’s age, weight, and condition, the name of the product and strength, and the time and amount of the product consumed. Don’t try to induce vomiting unless told to do so by an emergency care professional or by a poison control center. Unless the patient is having symptoms such as convulsions, vomiting, or is not alert enough to swallow, or the person is unconscious, immediately give the person milk or water. How well you can help depends on the amount of isopropyl alcohol accidentally swallowed, and how quickly the patient receives treatment. The quicker you seek medical help, the better the chance at recovery.
We all consume sugar in one form or another on a daily basis, the consumption of too much sugar can lead to health problems though. Artificial sweeteners a in almost any food product such as beverages, ice cream, chocolate, chewing gum, jams, yogurt and salad dressings. The first artificial sweetener, saccharin, was synthesized in 1879 and was well accepted during World Wars I and II, due to the scarceness of sugar and its low production costs. The motive for consumption, however, has shifted from cost reduction to calorie reduction. A profitable market for low calorie diet products evolved; artificial sweeteners were substituted for sugar, leading to the manufacturing and marketing of diet products.
