Eucalyptol Synthesis Lab Report
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Eucalyptol is quickly absorbed from the gastrointestinal tract. It is lipid soluble and absorption is enhanced in the presence of milk. Inhalation of the liquid is directly toxic to the lungs; however there is no data suggesting systemic absorption via lungs 8.
Eucalyptol undergoes oxidation in vivo with the formation of hydroxycineole which is
Excreted as glucuronide 9. The metabolism of eucalyptol was studied previously in rats and rabbits. Two alcohols, namely 2-hydroxy-eucalyptol and 3- hydroxy-eucalyptol, were excreted in the urine10, 11. It was also reported that eucalyptol is metabolized to several dihydroxycineoles, cineolic acids and hydroxycineolic acids after feeding brushtail possums and
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Lab Report 5: Acetylsalicylic Acid (Aspirin) Synthesis Name: Divya Mehta Student #: 139006548 Date Conducted: November 19th 2014 Date Submitted: November 26th 2014 Partner’s Name: Kirsten Matthews Lab Section: Wednesday 2:30 L9 IAs Name: Brittany Doerr Procedure: For the procedure, see lab manual (CH110 Lab Manual, Fall 2014) pages 96-98. Wilfrid Laurier University Chemistry Department. Fall 2014. Acetylsalicylic Acid (Aspirin) Synthesis.
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Extensive studies revealed that eucalyptol is considered to be a chemical which is safe when taken in normal doses. In higher doses, eucalyptol is hazardous via ingestion, skin contact or inhalation. Eucalyptol doesn’t show genotoxicity or carcinogenicity, but the substance may be toxic to the reproductive system. Repeated or prolonged exposure to the substance can produce damage to target organs 59.
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To purify and isolate trimyristin from a nutmeg, the sample of nutmeg was mixed and refluxed with dichloromethane before isolating and purifying the trimyristin through vacuum filtration and recrystallization. After refluxing the solution of dichloromethane and nutmeg, an intense amber colored solution was recovered. Through the process of vacuum filtration and recrystallization, a white, powdery and clumpy sample of solid trimyristin was collected. Of the 8.004 grams of nutmeg utilized in the experiment, 2.399 grams of trimyristin was collected after recrystallization, resulting in a 29.97% recovery in the experiment. By conducting a melting point experiment, the melting point for our extract of trimyristin was most accurately determined to be 50.3℃ - 51.6℃.
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