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Martha Cowles Chase

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Martha Cowles Chase, an American Geneticist, was known to be with Hershey during the conducting of their “Hershey-Chase Blender” experiment. With Chase, Hershey found a way to determine the role each of the phage components played in the process of replication. In their experiments done in 1951 and 1952, Hershey used radioactive phosphorus to tag the DNA and radioactive sulfur to tag the protein. (note that DNA contains no sulfur and the protein contains no phosphorus.) Hershey and Chase then allowed the marked phage particles to infect a bacterial culture and to begin the process of replication. This process was interrupted when the scientists spun the culture at a high speed with the use of a Waring blender. With this focus, Hershey
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