An unknown fact about the history of medical and scientific experimentation is the test subjects themselves. Prisoners have commonly been used for research in many unsafe settings, and because of these questionable conditions, many laws have been established to protect prisoners and any other human being partaking in experimentation. Some issues that arise concerning prisoner experiments would be informed consent, the safety of prisoners, and the protests against these experiments. The largest reoccurring problem throughout many prisoner experiments is the lack of informed consent. Prisoners weren’t usually referred to the test subjects that they truly were, but rather ,”...generally [referred] to [as] the test subjects as volunteers.” (Stobbe).