The genus Salvia comprises about 900 species distributed all over the world and is one of the major genera belonging to Lamiaceae family (1). Salvia species have been used since ancient times for different purposes, including perfumery industry and for culinary and therapeutic applications. These plants have been traditionally employed for their cerebrovascular and cardiac benefits, anti-inflammatory, antirheumatic, antimicrobial, tranquilizing, anticancer, antidiabetic, hepatoprotective and many other medicinal properties (2-4). Numerous phytochemical and biological studies have been carried out on a number of Salvia species. Flavonoids and terpenoids are the main secondary metabolites in Salvia species. Triterpenoids are major terpenoids …show more content…
S. suffruticosa aerial parts are used in some salads and foods in Turkey (6). To the extent of our knowledge, phytochemical studies on this species are confined to essential oil analysis. Camphor [48.5%], 1,8-cineol [18.6%] and camphene [7.9%] have been reported as main components of volatile oil from aerial parts of S. suffruticosa collected from east of Iran. In the mentioned study antibacterial potential of the essential oil has been assessed on some gram-positive and gram-negative bacteria and showed antibacterial activity against Staphylococcus saprophyticus, Salmonella typhi, Shigella flexneri and Escherichia coli but ineffective on Staphylococcus aureus and Staphylococcus epidermidis (7). In another study dichloromethane and ethyl acetate extracts of S. suffruticosa in concentrations up to 100 μg/mL have shown no inhibitory activity on acetylcholinesterase enzyme (8). In the present study we report isolation and structure elucidation of six compounds and essential oil composition, cytotoxic activity and antioxidant properties of the S. suffruticosa aerial