It is frequently believed that the Columbian Neo-Indian Exchange was one-sided. As I would visually perceive it as handed down to us by different historians. I bolster this suggestion in the light of the fact that the landscape of the incipient world have been undergoing a methodology for biological globalization since the landing of the Europeans voyagers in the late fifteen century. This encounter created a dramatic episode in the history of our world. The Columbian exchange as Alfred Crosby, called it, is the exchange of plants, human populations, diseases, and ideas between the incipient world and the old Hemispheres. The idea between the two areas circulated a wide variety of new crops and livestock which supported increase in population in both Hemispheres. It alludes to a time of social and organic trade between the Old world and the New Universes. Trades of plants, creatures, illnesses and innovations changed Europeans and local American’s lifestyle. Starting after Columbus’ disclosure in 1492, the trade endure during the time extension and disclosure. The Columbian Exchange affected the gregarious and social cosmetics of both sides of the Atlantic. Hence, headways in horticultural engenderment, advancement of fighting, augmented death rates and teaching are a couple of illustrations of the impact of the Neo-Columbian trade among the Indians and the Europeans. It all commenced in the year 1492 when Christopher Columbus and his crew sailed the Atlantic to