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Amygdala (Mepd): A Case Study

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An important part in the brain involved in memory, decision-making, and emotional responses is called the medial amygdala (MePD). The MePD is located within the temporal lobes of the brain and plays a major role in the life of complex vertebrates. MePD receives information pertaining to reproductive behavior from the hypothalamic portion of the brain (Johnson et al., 2008). The MePD is numerous in neurons and astrocytes. Astrocytes are neuroglial cells with many branches, or processes, that originate in the central nervous system. These neuroglial cells are believed to be involved in carrying nutrients and clearing neurotransmitters from within the synaptic cleft. Astrocytes are largely sex differentiated in size, and which hemisphere of the brain they are located in seems to have an influence on the complexity of the astrocyte.

The amygdala controls many social behaviors including fear, anxiety, and social interactions (Johnson et al., 2008). MePD is found to be largely sex differentiated in rats. Adult male rats have a much larger MePD volume than adult female rats (Pfau et al., 2016). …show more content…

This will result because the hormone levels of tfm rats are stronger or equal to that of a female rat but weaker compared to a male rat. The levels will be tested by eliminating the influence of androgens by castration and adding different amounts of androgens back into the body of the subject. After adding different amounts of androgens back into the body, we can evaluate and record the behavior changes to determine if there is any visible change in the behavior. After recording visual effects of the subject, we can then look at the change in astrocytes within the brains of the tfm rats. This study will determine how the androgens and the ARs effect astrocytes within the brain of the

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