Clostridum Failure
This time with stomach pains, diarrhea, and bloating. Viewing the bacteria in their gut during week 7, there is a new type of bacteria called C. difficile. This bacteria can cause deadly infections. It was developed in this persons gut becuase of all the empty space. It invaded it's way into their gut and rapidly started to multiply.
The purpose of this lab report is to employ a myriad of skills, tools and, methods learned throughout this semester to perform the appropriate tests for the identification of the assigned unknown bacteria. Add more background information here!!! The most important tools and techniques used during this identification include aseptic technique, microscopic examination and, the use of selective and differential media. Aseptic technique is an important tool for microbiologists. It is imperative that aseptic technique is maintained throughout the length of any test to avoid any cross-contamination that may lead to inaccurate results.
Q1A: What is the mechanism of action of colistin? Colistin is an antibiotic that works best against Gram-negative bacteria. It works by binding to LPSs (lipopolysaccrides) and phospholipids in the outer cell membrane of the bacteria. This, in turn, disrupts the outer cell membrane by displacing cations and leaking the intracellular contents, combining it with outer cellular contents, causing the bacteria to be unable to differentiate the bacteria’s intra and outer cellular contents from one another.
Aza is so focused on a very rare disease called Clostridium Difficile (diff C) that she is
The morality of Healthcare acquired infections has increased tremendously whereas; both inpatient and outpatient clients have been infected during a hospital visit. These infections has weaken the sick which may lead to additional medications, or surgery, and extended hospital stay. According to (CDC 2002), healthcare acquired infections are result of unhygienic practices in medical field. This includes ambulatory surgical centers, hospice center, nursing homes and rehabilitation centers.
Broad spectrum antibiotics tend to kill the bodies normal flora, which then allows bacterium’s like C. difficile to spread and grow rapidly in its vegetative state. Toxin A (enterotoxin) is then produced causing diarrhea, followed by toxin B (cytotoxin) which causes damage to the mucosal cells. Toxin A and B also induce the secretion of cytokines into host cells, which often cause an acute neutrophilic inflammatory infiltrate. Together, these toxins enable the interruption of tight junctions in the intestine and cause inflammation of the colon leading to an extensive amount of fluid secretion (diarrhea). A third toxin has recently been discovered in newer strains of this bacterium called the binary toxin.
The subject of my teaching project is a disease known as clostridium difficile or a disease more commonly known as c diff. The patient who was being taught, was a forty-three-year-old, white male, who had no previous exposure to clostridium difficile. When conducting the teaching, the patient had a couple of teaching points he needed to adopt into his care. When in the hospital, the patient should help with reminding healthcare workers and visitors about the importance of hand washing, and wearing gowns and gloves when in contact with said patient. If the patient was to be sent home, there were a few things to keep in mind.
MEDSURG Nursing, 23(3), 187-188. Farber, J., Illiger, S., Gartner, F. B., Lutz, v. M., Lohmann, C. H., Bauer, K., . . . Geginat, G. (2017). Management of a cluster of Clostridium difficile infections among patients with osteoarticular infections. Antimicrobial Resistance and Infection Control, 6 doi:http://dx.doi.org.southuniversity.libproxy.edmc.edu/10.1186/s13756-017-0181-4 Wang, J., Quan, K. A., Tjoa, T., Yim, J., Dickey, L., Chang, J., ... & Gohil, S. K. (2016, December).
Clostridium difficile infection and transmission prevention continues to represent а difficult and serious challenge in patient safety and infection prevention. A single inpatient Clostridium difficile infection costs more than $35,000 in average and the estimated yearly cost burden for the health care system is more than $3 billion (MedPage Today, 2012). The epidemiology of Clostridium difficile infection is continue to change, and its presence in the community and the healthcare settings has caused healthcare personnel continue to re-evaluate approaches and perspectives. There are many risk factors for Clostridium difficile infection such as an exposure to antibiotics, advanced age, and hospitalization.
In UC, the colonic mucosa will undergo recurrent inflammation (Meier & Sturm, 2011). Inflammation occurs in the distal to proximal colon segments (Meier & Sturm, 2011). The clinical feature of UC is the presence of bloody diarrhea (Danese & Fiocchi, 2011). Mucous may or may not be present in the diarrhea (Danese & Fiocchi, 2011). Patients with UC usually present with an urgency to evacuate the bowels, bleeding from the rectum, diarrhea, and abdominal pain (Ford, Moayyedi, & Hanauer, 2013).
Dientameoba fragilis consideration in the differential diagnosis and association with irritable bowel syndrome. Roma Uthappa1 1University of technology Sydney, Broadway, Australia Abstract On average 10 % of the population would have symptoms of irritable bowel syndrome at any given time and approximately 200 people per 1 0 0, 0 0 0 will be given the diagnosis of irritable bowel syndrome through the course of a single year (Choung and Locke, 2 0 1 1). These patients will suffer from symptoms such as altered stool pattern of constipation and diarrhoea, abdominal pain, weight loss, vomiting, bloating, and nausea (Engsbro et al., 2 0 1 2).
It is almost impossible to know all areas of any given environment where you can become contaminated by this disease. Crohn’s is most likely to develop in urban and industrialized areas (Mayo Clinic Staff, 2014). Many are unaware that people who smoke put the environment at an even higher risk, substances from smoking can increase the risk of an individual and individuals around them getting the disease. Studies have shown that people are put at an increased risk of developing Crohn’s disease from smoking, and research shows that smoking can lead to severe symptoms of the disease (Smoking and IBD, 2014). Bacteria and viruses are spread throughout an environment on a daily basis, which can trigger symptoms of an individual with the disease.
The bad: Lactose intolerance (where you lack the enzyme lactase in your intestine) or coeliac disease (a sensitivity to gluten, found in wheat and some other cereal grains). Other causes of diarrhoea include irritable bowel syndrome (IBS), especially if there is cramping or other abdominal symptoms, says allergy and immunology specialist Dr Alex
Crohn 's disease is a type of inflammatory bowel disease which means it can take place anywhere from the mouth to the anus(GI tract). The most common areas is the ileum and the colon. Crohn 's disease appears when regular bacteria that helps with breakdown of food is misunderstood for something trying to harm the body. Then the antibodies create inflammation in that specific area. Which precedes as a chronic disease that deals with not only inflammation but ulcers created in the tissue.
There are a myriad of causes of diarrhea. The most common of these is an infection of the bowels
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