An example of a disease that results from an imbalance in a negative feedback mechanism is Cushing’s Syndrome/disease. Cushing’s Syndrome occurs when our body produces high levels of a glucocorticoid hormone called cortisol. When produced at the ideal level, cortisol is very beneficial to our body for it helps regulate blood pressure and the immune system. A normal production of cortisol begins when a hormone (produced in the hypothalamus) called corticotropin-releasing hormone (CRH) stimulates cells in the pituitary gland that make the hormone called adrenocorticotropic hormone (ACTH). Adrenocorticotropic is then carried through the bloodstream to the adrenal gland where cortisol is produced. The amount of cortisol that is produced depends