Coronary heart disease starts to develop at a young age when plaque can start to develop in the blood vesicles walls. As your get older, the plaque builds up, inflaming the blood vesicle walls, making your arteries more prone to blood clots and giving you a higher risk for a heart attack. Soon enough, the plaque starts to release chemicals for healing but ends up making the artery sticky, resulting in things like calcium sticking to your blood vesicle walls. The heart then tries to compromise by making new vesicles to do the job of the damaged ones, but in times of stress the new vesicles may not be able to provide enough oxygen-rich blood to your heart. If you have a big enough blood clot that totally shuts down your artery, you have a heart