Efficacy of topical cyclosporine 0.05% eye drops in the treatment of dry eyes
Haitham Y. Al-Nashar
J Egypt Ophthalmol Soc 108:233?236
Purpose: The aim of the present study was to detect the effectiveness of cyclosporine 0.05% eyedrops for treatment of patients with dry-eye disease.
Patients and methods: A total of 35 eyes of 20 dry-eye patients were included in the present study. Ten patients (20 eyes) had dry eyes associated with systemic rheumatologic disease (Sj?gren?s syndrome), five patients (10 eyes) had dry eyes after undergoing laser in-situ keratomileusis, and five patients (five eyes) had dry eyes after cataract surgery. Detailed history taking with complete ophthalmic examination was carried out for all patients. Break-up time (BUT) test and Schirmer?s test were done for all patients. The patients were examined for ocular symptoms of dry eyes (eye pain, eye burning, and sensation of
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Patients and methods
In this study, 35 eyes of 20 patients with dry-eye disease were included. Ten patients (20 eyes) had dry eyes associated with systemic rheumatologic disease (Sjogren?s syndrome), five patients (10 eyes) had dry eyes after undergoing laser in-situ keratomileusis (LASIK), and five patients (five eyes) had dry eyes after cataract surgery. The patients were treated with cyclosporine 0.05% eye drops.
Detailed history was taken from all patients, including age, sex, previous medical and ocular diseases, and duration of symptoms. For all patients, routine ophthalmic examination was carried out. Slit-lamp biomicroscopy, break-up time (BUT) test and Schirmer?s test were also conducted. Before the beginning of the treatment the patients were examined for ocular symptoms of dry eye (ocular pain, burning, and foreign body sensation). Each symptom was given a score from 0 to 1 so that the ocular symptoms were given a score from 0 to