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Glioblastoma Research Paper

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Glioblastoma Multiformes
The nervous system is divided into two parts; the central nervous system and the peripheral nervous system. The central nervous system is the brain and spinal cord, and the peripheral nervous system is the nerves outside the brain and spinal cord. The peripheral nervous system is involved in movement, sensing, and the functioning of the internal organs" Cancer.Net. 2 July 2012. Nervous system cancer is the second most common type of childhood cancer after leukemia.Walter, Andrew. KidsHealth - the Web's Most Visited Site about Children's Health. The Nemours Foundation, 1 Mar. 2013. Brain cancer is part of the nervous system cancer category and there are two main types: primary and metastatic. Primary brain tumors originate …show more content…

Both primary and metastic can either be benign or malignant, meaning they can be noncancerous and cancerous. Glioblastoma multiforme , Astrocytomas, Meningiomas are all very closely related but have characteristics to distinguish them. Meningioma is the cancer that occurs on the thin outer cover that lines the spinal cord and brain (Meninges). There are three layers; the dura matter, the arachnoid, and the pia matter. Astrocytomas are malignant tumors that that originate in astrocytes. Astrocytomas get their name because they are made up of star-shaped cells called astrocyte. They come from glial cell that support the nerve cells of the brain. Right under the category of Astrocytomas are Glioblastoma Multiformes that are the most aggressive form of astrocytomas and is also the most common type. They are cancer of the glial (supportive tissue of the brain) Swierzewski III, M.D., Stanley J. Glioblastoma multiforme is a malignant astrocytoma. These cancerous tumors occur in primarily adult males over the age of 50. Those with the tumor at a younger age have a better survival rate. Symptoms include headaches, seizures, or change in mental status. "Astrocytomas and Glioblastomas." Glioblastoma multiformes occur in …show more content…

"From the Blog." Defeat GBM. Web. 22 Oct. 2015. More research going on include new immune-based treatments that are currently in development. This organization features information on brain cancer and immunotherapy clinical trials for brain cancer patients, and highlights the Cancer Research Institute’s role in working to bring effective immune-based treatments to people with brain cancer. It is estimated that 1 in 161 individuals born today will develop brain or nervous system cancer at some point in their lives. In the U.S., 22,850 men and women are diagnosed with cancer of the brain and nervous system every year, and 15,320 deaths are caused by the disease. Although significant advances have been made in understanding the biology of brain cancers—as well as in tumor diagnosis, treatments, and quality of life of patients with the disease—the mortality rate for brain cancer has remained steady for more than 30 years. The cause of brain tumors is not yet understood. Glioblastoma (GBM) is the most dangerous and aggressive form of brain cancer. GBM patients typically have short life expectancies; few will live to see three years after diagnosis. For newly diagnosed GBM patients

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The prognosis who have contracted GBM is not optimistic, due to it being a fast growing, highly malignant tumor in the brain. The survival rate is considerably low, with only around 10% of patients surviving for five or more years even with proper treatment. Median survival of Glioblastoma is only 14.6 months with treatment while a two year survival rate is around 30%. Interestingly, children with high grade brain tumors such as glioblastoma have seen a five year survival rate at around 25% (“Glioblastoma (GBM)”, American Brain Tumor Association). A major pattern seen in those diagnosed with glioblastoma is that 80% of the patients had an extra copy of chromosome 7

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