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Lou Gehrig's Disease

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Amyotrophic lateral sclerosis known by an another name as Lou Gehrig’s disease affects a maximum of 2,000 people a year from the age of 50 - 70 years. The word amyotrophic was derived from the Greek descendants. The Signs of lower motor neuron and upper motor neuron damage is not detailed by any other disease process other than ALS. It attacks the neurons present in the CNS. They function in transmitting messages from the central nervous system to the voluntary muscles - the ones which can be controlled, like limbs. At earlier stage, they cause mild muscle problems. Some patients may show symptoms like trouble in walking, trouble in writing and speech problems. Gradually the strength is lost and the patient has difficulty in movements. When …show more content…

It was described in the year1869 by neurologist named Jean-Martin Charcot. It is also known as Lou Gehrig’s disease, which affects around 2,000 people per year in England and Wales, with a peak age of onset between 50 years and 70 years(1) In the United States when a baseball player named Lou Gehrig was diagnosed with the disease in 1939. It is also named as Charcot disease to honor the first person to describe the disease, Jean-Martin Charcot .It causes nerve cells to gradually break down and die. Amyotrophic comes from the Greek language. "A" refers to no, "Myo" to muscle, and "Trophic" to nourishment meaning "No muscle nourishment." When a muscle gets no nourishment, it "atrophies" or wastes away. The word "Lateral" are the areas in a person's spinal cord where the portions of the nerve cells that signal and control the muscles are located. ALS occurs more in men than in women by a factor of between 1.2 and 1.5. (2) As the muscle degenerates it causes scarring or hardening (sclerosis) in the particular region. Degeneration of the motor neurons in ALS eventually leads to their death of the neurons. When it occurs, the ability of the brain to initiate and muscle movement control is lost. Since voluntary muscle action gets affected, people may lose their ability to speak, eat, move and breathe. It may also be said that it is neurodegeneration with prodilection for the cortico motor neurons in the motor cortex and the bulbar and spinal motor neurons. Mainly the motor neurons are selectively targeted for degeneration in this disease. In 1993, missense mutations in the gene which encodes the antioxidant enzyme Cu/Zn superoxide dismutase 1 (SOD1) were discovered in subsets of patients diagnosed with familial ALS .Its pathogenesis is complex and multifactorial and disease commonly characterized by stiff muscles, muscle twitching, and gradually worsening

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ALS became known as “Lou Gehrig disease”. Gehrig said his final goodbyes to his fans and baseball on July 4, 1939, with a short tearful speech. " Today I consider myself the luckiest man on the face of the earth." Thanking his parents, wife,and teammates with "I might have been given a bad break, but I have an awful lot to live for. Thank you."

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“Lou Gehrig’s Career, and his Disease” Do you know where the name Lou Gehrig’s Disease came from? Most people know this Disease as ALS (amyotrophic lateral sclerosis) which means the same thing. Effects of this disease: is symptoms that may include fasciculations, cramps, tight and stiff muscles. Lou Gehrig Was 36 when he had this disease. Lou to retire early because of this disease, Lou died two years after retiring from this disease.

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Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord. ALS is also named Lou Gehrig’s disease because he was the first person to bring ALS to a national attention in the 1930’s. Lou Gehrig’s amazing professional baseball career was ended short by this horrific disease. There are multiple treatments for ALS, but no cure for this fatal disease. In 2014, ALS was brought to major attention by the ALS Ice Bucket Challenge.

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According to WebMD, the first type of spinal muscular disease is the most serious variant due to the fact that most children with type 1 fail to live past two years of age from breathing issues because the muscles that control breathing are feeble. Symptoms of type 1 include limp arms and legs as well as the trouble swallowing. Moreover, type 2 spinal muscular atrophy occurs with children from six to eighteen months old. According to the National Organization for Rare Diseases, children with type 2 are able to sit on their own, but fail to walk more than 10 feet, however, once they mature to a teenager, they will be unable to sit independently. A symptom common for people diagnosed with type 2 is the fingers quivering (National Organization for Rare Diseases).

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Introduction Alzheimer’s is a chronic neurodegenerative disease that usually starts slowly and gets worse over time. The most common early symptom is difficulty in remembering recent events or short memory loss. As the disease advances, symptoms can include difficulty with language, disorientation, mood swing and behavior problems. As a person 's condition progressed, they often withdraw from friends and family. Slowly, bodily functions deteriorated and eventually death occurs.

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“So, I close in saying that I might have been given a bad break, but I’ve got an awful lot to live for,” Lou Gehrig made that as his closing remarks in his “Farwell” speech two weeks after announcing he had ALS (“Farewell”). ALS, or Lou Gerhig’s disease, is a degenerative neurological disease that weakens and, eventually, renders muscles useless and has many other symptoms and causes that are still being discovered, including brain concussions from football and other sports. Described by scientists as far back as 1824, it wasn’t until 1869 when French neurologist Jean-Marie Charcot first wrote and published reports of the characteristics linked to ALS (“About,” ALSA.org) (“About,” Wordpress). It wasn’t until when Lou Gehrig was diagnosed with the disease. In 1938, after having a difficult time with playing baseball, Gehrig visited the Mayo Clinic in Minnesota, where he was diagnosed with ALS (“Lou Gehrig”).

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After being diagnosed Lou Gehrig passed away about two years later, he was diagnosed in 1939 and later passed in

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Now called Lou Gehrig’s disease, which is a nervous system disease that weakens your muscles, and impacts physical function. On July 4, 1939, the Yankees decided to have a day in honor of Lou. All the teamates and fans stood in his honor. Soon after in that december he was inducted into the hall of fame. Shortly after, on June 2, of 1941 he took his last breath.

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“Today I consider myself the luckiest man on the face of the earth” (“Lou”). This was said by Lou Gehrig in 1939 at his Hall of Fame ceremony (“Lou”). He had amyotrophic lateral sclerosis, also known as ALS or Lou Gehrig disease (“ALS”). To begin, amyotrophic lateral sclerosis (ALS) is broken into three different terms (“ALS”). The “a” in amyotrophic means no or negative (“ALS”).

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The life of Lou Gehrig will always be remembered. He is one of the greatest 1920’s icons anyone is ever going to see. He was one of the first to get ALS which is also name after him as “Lou Gehrig’s Disease”. One of the most famous quotes he made before he died of this was on the 4th of July where he said, “Fans, for the past two weeks you have been reading about a bad break I got. Yet today I consider myself the luckiest man on the face of the earth”.

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Lou Gehrig had to retire from the MLB because he was diagnosed with ALS, a disease that slowly starts to make every muscle in your body fail, until you pass away. To this day, there is

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ALS affects both the upper and lower motor neurons in the body. The upper motor neuron, found in the

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This ultimately leads to the inability to move and function, and soon after, death. During his time at Columbia University he joined a fraternity Phi Delta Theta. When he was diagnosed with ALS and past away with his legacy, Phi Delta Thetas nationals made ALS their national philanthropy. I am lucky enough to be apart of such a great fraternity and support the ALS foundation to stop this terrible disease. Lou Gehrig came from nothing and turned his life around into something great.

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These general objections then form into more clear shortcoming or decay that may bring about a doctor to suspect ALS ("Amyotrophic"). The body parts indicating early side effects of ALS rely on upon which muscles in the body are influenced. Numerous people first see the impacts of the sickness in a hand or arm as they experience trouble with straightforward undertakings requiring manual ability. In different cases, manifestations at first influence one of the legs, and individuals experience clumsiness when strolling or running or they see that they are stumbling or staggering all the more regularly. At the point when side effects start in the arms or legs, it is alluded to as "appendage onset" ALS.

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