Organic Synthesis Research Paper

Organic synthesis is a special branch of chemical synthesis and is concerned with the production of organic compounds via organic reactions [1]. Organic molecules can often contain a higher level of complexity compared to purely inorganic compounds, so the synthesis of organic compounds has established into one of the most important sides of organic chemistry. The necessity of using synthesis to prove the structure of a compound lost after the introduction of the instrumental methods of analysis, although many still commonly synthesize natural products. The synthesis of these natural products increases the available supply of the compounds for further study or use. Researchers also use synthesis to attempt to prepare unknown compounds that

They are classified under flavonoids (2) type and they participate in the biosynthetic pathways of flavonoids and isoflavonoids(3) and act as their precursor [3]. Chalcones can be prepared by an aldol condensation between a benzaldehyde (4) and an acetophenone (4) in the presence of sodium hydroxide as a catalyst. This reaction can work without any presence of solvent, it is a dry state reaction. The reaction between substituted benzaldehydes and substituted acetophenones has been used to support green chemistry in chemistry education [4]. Compounds with backbone of chalcone have been reported to possess various biological activities such as antiviral, antimicrobial [5], anti-inflammatory, antioxidative [6], anticancer and antitumour [7].

Flavonoid is natural phenolic compound, any member of a class of biological pigments containing no nitrogen that are found in many plants [8]. Flavonoids present naturally in fruit, vegetables, and beverages such as tea and wine. Research in the field of flavonoids has increased. Several other potential beneficial properties of flavonoids have since been find out. An important effect of flavonoids is the scavenging of oxygen derived free radicals. In vitro experimental systems also showed that flavonoids possess antiinflammatory, antiviral, and antitumour properties

The extracts and metabolites of Artocarpus especially from leaves, bark, stem and fruit possess several useful bioactive compounds and recently additional data are available on manipulation of these compounds in the various biological activities including antibacterial, antitubercular, antiviral, antifungal, antiplatelet, antiarthritic, tyrosinase inhibitory and cytotoxicity [12]. Several pharmacological studies of the natural products from Artocarpus have conclusively recognised their mode of action in treatment of various diseases and other health benefits. Also, Jacalin, a lectin present in seeds of this plant has a wide range of biological