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Cholesterol Research Paper

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Cholesterol is a soft, waxy substance that's stored in the fat (lipid) content of one's blood stream. It's actually important to have a certain amount of "good" cholesterol in one's system. Cholesterol, and our other body fats, cannot dissolve in our blood. They must be transported by special carriers called lipoproteins. While there are numerous kinds (too many to cover here), the two that are most important are the high-density lipoproteins (HDL) and the low-density lipoproteins (LDL). There is a third kind, which is referred to as Lp(a), which can increase one's risk of heart attack and stroke. We'll cover that one here, as well. HDL, LDL, & Lp(a)...What ARE These? High-density lipoproteins (HDL) are known as "good cholesterol". …show more content…

This is a generic variation of plasma (the "fluid" which carries the blood cells through one's blood stream) LDL. When one's Lp(a) level is higher, one can more quickly develop the plaque build up which physicians and specialists refer to as "arthersclerosis". Although there has been no conclusive evidence drawn as to WHY Lp(a) contributes to the increased risk of heart disease, it is commonly believed that the natural lesions which occur in our artery walls may contain substances that interact with it. This may lead to the build up of the fatty …show more content…

Even a moderate amount of daily activity can help to increase the movement of blood through one's body. Physical activities such as leisurely walking, gardening, light yard work, housework and slow dancing are often prescribed as ideally suited for those who need a daily routine to help control the cholesterol levels. A more intense regimen can include brisk walking, jogging, swimming and weight-lifting. Aerobic exercising is an excellent way to increase one's breathing and heart rates. Side benefits of a regularly scheduled exercise program can include weight control, reducing one's risk of developing diabetes, and helping to keep one's blood pressure at a healthy level. Regular moderate to intense exercise can also help to strengthen one's heart and lungs. To Smoke or Not to Smoke... Most physicians and specialists recommend that no one smoke. And it has been proven that tobacco smoking increases the risk of heart disease. One's intake of oxygen, which is a necessary component for good vascular circulation and health, is drastically reduced. Plus, smoking is detrimental to HDL cholesterol levels and increases the possibility of blood clots, not to mention the risks of causing cancer in one's

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This protein binds to the LDLR, which undergoes the exact same receptor-mediated endocytosis pathway. This leads to PCSK9 and LDLR being degraded in the lysosome of the cell (Tavori, et al., 2013). In this process, PCSK9 is actually decreasing the number of opportunities for LDL to leave the bloodstream due to the decreased number of LDLR available that it can bind to. There can be a gain-of-function mutation on the PCSK9, which is a very rare form of hypercholesterolemia (Tavori, et al, 2013). This mutation causes an increased regulation rate of PCSK9, which means there is more availability for PCSK9 to bind to LDLR and less availability for LDL to bind to LDLR, thus increasing cholesterol concentration in the

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The benefits above are general. Let's examine the more specific benefits of exercise on specific parts of the human anatomy, as described by Goldberg and Elliot: Exercise prevents heart disease! The average ratio of total cholesterol to HDL cholesterol (good cholesterol) is about 4.5. If this ratio doubles or reaches 7, you double your chances of developing coronary heart disease.

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In addition, olive oil is a good food additive which is well-known to lower LDL "bad" cholesterol while increasing the amounts of HDL "good" cholesterol. It is equally considered an excellent source of carotenoids, tocopherols, and phenolic compounds which have powerful antioxidant properties to effectively fight against

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I’ll get to that in a moment but first… What is cholesterol? Cholesterol is a waxy substance

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Fat-O-Phobia This was an interesting point made in the reading, it outlines how today we are in a way scared of fat and try to avoid it at all cost. Ratey pointed out that cholesterol is thought to be the main reason for most heart diseases “Dietary cholesterol, for instance, has an insignificant effect on blood cholesterol. It might elevate cholesterol level in a small percentage, but for most of us, it’s clinically meaningless” (Ratey, 2015, p. 83).

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Public Service Announcement As many people are aware, smoking is a very big issue. It can damage your heart and blood circulation, causing all sorts of issues. Yet we continue to let it be legal and sold in many, many stores. Once you start smoking you become addicted to cigarettes.

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blood cells) have a constant interaction, but this interaction increases with elevated cholesterol levels. As the cholesterol levels increase, the monocytes begin to attach onto the endothelium, where they are transformed into macrophages. These macrophages begin to oxidize the LDL and they become toxic to the endothelium which leads to platelet adhesion and aggregation and fibrin deposition. The macrophages begin to ingest the oxidized LDLs transforming them into foam cells, which begins the formation of the lipid core of unstable plaques. Damage to the vessel wall causes macrophages, lipids and cholesterol to form a plaque leading to the last level of atherosclerosis, complicated lesions which includes hemorrhage, ulcerations and scar tissue

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2.4 NAFLD and the metabolic syndrome The metabolic syndrome is a constellation of closely related cardiovascular risk factors. The International Diabetes Federation defines metabolic syndrome as the presence of central obesity based on ethnic specific cut-off for waist circumference, plus two or more of the following: raised triglycerides, reduced serum high-density lipoprotein (HDL) cholesterol, raised blood pressure and raised fasting plasma glucose.(42) Insulin resistance is an important feature of metabolic syndrome.

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Cholesterol is actually not that bad for the body in some cases. That doesn’t mean it is sometimes bad though. Like for example it insulates nerve cells in the brain and provides cell membrane structure. The “good” cholesterol is made by the nerve and liver cells. It kind of looks white and waxy.

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Over time the ongoing damage to people’s blood vessels cause peripheral artery disease. Not only does smoking impact people’s cardiovascular health, but it also effects the health of those that don’t smoke because their around it. The exposure to secondhand smoke carries the same risks to non-smokers to someone that does smoke. Smoking effects the integumentary system by skin changing. Substances in tobacco smoke can really change the structures of people’s skin over time.

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Any activity that takes the heart rate up will increase the metabolic rate, which will raise the energy requirement and mobilization of fat, which in due course will reduce the blood pressure. Smoking is Indeed Hazardous: Although the evidence is a bit smoky, tobacco and nicotine has been found to cause a temporary rise in blood pressure. And we are not going to get into the other health issues that the so called cancer sticks can

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(1) First, I will talk about why we should exercise, (2) how to make time for exercise, and (3) different alternatives to exercise. Transition/Link: First, I want to discuss why everyone should attempt to exercise. Exercise can help to increase energy and help maintain or decrease blood pressure levels. Exercising regularly can help you lose weight and keep it off. According to Exercise Makes You Younger”, published in Nursing Update "Heart disease and stroke are two of the leading causes of death in the world.

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When eating cholesterol that is unneeded this will block the valves in the heart and prevents blood flow to the rest of the body, which can cause you to have stroke or heart attack. You should decrease the amount cholesterol you have and eat more fruit and veggies. You need to have a variety in color with every meal you eat to get the nutrients you need to help your body grow and develop. Fruits and veggies provide import vitamins that the body needs to function properly and if you don’t get enough it can cause your organs to function improperly. The water intake you have is very minimal, so you need to boost this area up.

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HDL cholesterol is the “good cholesterol” or the cholesterol that gets taken in by the liver to be recycled or destroyed. Low carbohydrate diets are easy to be controlled because people eat mostly everything except snacks, bread, and anything with many carbohydrates in them. Low carbohydrate diets make it easier to control cholesterol levels than conventional diets because there is no difficult mathematical struggle of counting everything that is

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While modifying our diet can certainly help us decrease our risk for heart disease, studies have indicated that people who don 't exercise are at an even greater risk for heart disease. (factual example - Camenzind) Satisfaction II. Fortunately, there is a simple, effective exercise that we can all do. A.

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