Amine Essays

Chiral phosphorus compounds are of great important in the fields of pharmaceutical chemistry1, materials2 and typically used as versatile ligands3 or oganocatalysts4 in asymmetric catalysis. Generally, transition-metal1a,5 or inorganic base6-promoted asymmetric P-C bond formation constitutes one of prominent strategy for the preparation of chiral phosphorus compounds possessing chiral centers at phosphorus and/or carbon atmos. In the recent years, organocatalytic asymmetric P-C bond formation from

Amino acids are the building blocks of life. They are tiny molecules that contain nitrogen. There are twenty-two naturally occurring amino acids, twenty of these are found in human cells. These twenty are the building blocks of the human body. They hook together to form enzymes, hormones, immune molecules and neurotransmitters. The human body has the ability to make some of these, but others must come from food. Non-Essential From the time humans are infants, their bodies produce non-essentials

2. Experimental Part 2.1 Materials Starting deacetylated chitosans (Mws, 129.4 and 236.7 kDa) were prepared as described previously by Tiera et al. [27] from commercial chitosan (degree of deacetylation (DD) 86 %) purchased from Polymar (Fortaleza, Brazil). 2-Chloro-N,N-diethylethylamine hydrochloride (DEAE), folic acid, sodium acetate, acetic acid, dicyclohexyl carbodiimide (DCC), N- hydroxylsuccinimide (NHS), dimethylsulfoxide (DMSO) were purchased from Aldrich Chemical Co. All solvents were reagent

Introduction Chiral molecules chemical structures that are non-superimposable mirror images of one another, much like the way a person’s hands are. Also known as stereoisomers, these compounds have the same molecular formula with different spacial orientation. Each chiral molecule contains a pair of enantiomers, each of which represents the two structures for each molecule (ie left hand and right hand). Chiral molecules play a huge part in pharmaceutical compounds, making up 56% of the drugs currently

Amino acids are organic compounds that are the building blocks for proteins (Bruice). They are composed of a carboxylic acid with a protonated amino group and a hydrogen on the alpha carbon (Bruice). Amino acids have various side chains that provide proteins with great structural diversity, and in turn, functional diversity (Bruice). Amino acids can be divided into polar, non-polar, acidic, and basic (Bruice). The amino acids used in this experiment are Phenylalanine, Leucine, Lysine, and Alanine

Introduction Acetanilide is a white, crystal-like compound which is the resultant of the synthesis of aniline and acetic anhydride. In 1886, acetanilide was implemented into medicinal practice by P. Hepp and A. Cahn and was the first derivative of aniline that was found to be a pain-reliever. The compound has also been utilized in the manufacturing of other drugs such as penicillin and sulfonamide drugs. Acetanilide can be used as an inhibitor for the decomposition in H2O2 solutions and in the production

2. REVIEW OF LITERATURE 2.1. Biogenic Amines: 2.1.1. Origin of biogenic amines: Pipek et al. (1992) recorded that biogenic amines are compounds commonly present in living organisms in which they are responsible for many essential functions. They are present in low concentrations in human, animals and plants for regulating functions, acting on the nervous system. Therefore, biogenic amines are naturally found in many foods including meat and can be produced in high amounts by microorganisms through

In the end, it was concluded that Unknown 30A may have a low molecular weight and was an amine because it turned the red litmus paper blue, after being soluble in water. Therefore, the solubility of the unknown occurred due to weak intermolecular attractive forces of hydrogen bonds. Small amines form hydrogen bonds in water. As a result, the litmus paper turned red to blue because the amine accepted protons from their bond with water molecules, and was basic. Functional group tests were performed

Experiment # 3 – Resolution Of ( )- -Phenylethylamine Name: Krishna Binu Class: Chem 2020 Due Date: October 23, 2015 Table 1 Shows the experimental results. Name Result Mass of Amine (g) 3.32 Mass of Salt (g) 1.26 Observed Rotation of Isolated Amine (Degrees) -36.33 1) Draw the chemical structures of the two diastereomeric salts produced in Part A using a proper perspective (line-angle) representation. Please note: (+)-tartaric acid has the (R,R) configuration

was formed. i) The theory stated that the mood is determined in the brain by biogenic amines – complex chemicals who’s structure resembles that of ammonia. ii) Before antidepressants, amines were involved in the regulation of a variety of functions; from heart rate and stomach motility, to alertness and sleep. (1) Iproniazid and Imipramine concluded that amines regulated mood but it could not be proved. (a) The amine hypothesis could not support the effects of the drugs. The drugs did not have an immediate

1967). Synthetic azo dyes are widely used in different industries. Azo dyes have characteristic chemical structure that is called (azo) bond R-N = N-R'. Azo dyes are compounds consisting of a diazotized amine attached to an amine or a phenol and contain one or more azo linkages. Aromatic amines are essentially the products of azo dyes. Nowadays there are more than 3000 recognized azo dyes which are present in different industries such as textiles, paper, food, cosmetics, and pharmaceutical industries

For this experiment, the preparation and chemiluminescence of luminol was observed. The purpose of this experiment was to synthesize luminol and observe its chemiluminescence. Luminol’s chemical structure is comprised of a cyclic diamide moiety. The synthesis of luminol began from 3-nitrophthalic acid which is a dicarboxylic acid. The first step of the synthesis was the double amination of the carboxylic acid functional groups with hydrazine to construct the cyclic diamide substructure which was

At the start of my freshman year of college, I decided to dive straight into organic chemistry. Having a preview of the subject in a special offered course at the end of my senior year of high school intrigued me and I wanted to learn more. Despite academic advisors telling me I would struggle and possibly fail at taking such a notoriously difficult class at the beginning of my academic career, I felt confident in my ability to take it and be successful, and I was right. During the second part

light sensitive, especially UV and undergoes fast photolytic degradation.The mechanism of NDMA formation is related to the reaction of secondary amines with nitrite, wherein NO+ plays a particular role. Tertiary amines do not react with nitrite. Secondary amines on reacting forms appropriate nitrosoamines (Andrzejewski et al,2005) But with primary amines, the reaction led to the formation of ammonia, with NDMA as intermediate

The recent spurt in terrorist activities involving TNT as an explosive and its widely reported role as an environmental contaminant made it an analyte of prime concern for the scientific community dealing with environmental problems and national security [1-3]. Consequently, there is an imperative need for rapid and steadfast methods of trace detection of TNT, for screenings in airports, analysis of forensic samples, and environmental analysis [4-5]. Traditionally, x-ray based instruments and trained

Aldol condensation In the aldol condensation the α-carbon of one aldehyde or ketone molecule adds to the carbonyl carbon of another. The base is most often used is -OH. The product is a β-hydroxy aldehyde or ketone, which in some cases is dehydrated during the course of the reaction. Even if the dehydration is not spontaneous, it can usually be done easily, since the new double bond will be in conjugation with the C=O bond.   Ritter Reaction Alcohols is converted by a strong acid to a carbocation

Dragon, Boy, dope, H, Smack or more commonly ‘Heroin’ CAS: 1502-95-0 Chemical Structure of Diamorphine   Identification and Description of Structural Features3 The functional groups present in diamorphine hydrochloride are esters, ethers, alkenes, amine and an aromatic ring. Esters There are two esters present in diamorphine hydrochloride which are formed by acetylating morphine. Esters have the RCOOR’ functional group, as depicted in the diagram. Esters are formed by reacting an acid and an alcohol

a more efficient production, Merck and Codexis, two pharmaceutical companies, mutated transaminase enzyme to catalysis the transfer of amino group. The use of this enzyme helps improve the yield for sitagliptin by converting ketone to the desired amine

used qualitatively and quantitatively. For example, chromatographic visualization for the former and peptide sequencing for the latter. The colors produced are because of the amines reacting with the ninhydrin. Different amines produce different colors. For example, α-amino acids produce a blue-purple product while secondary amines like Proline produce a yellow-orange product (Hunt, n.d.). In the Ninhydrin Test, the electron deficient polar carbonyl carbon is attacked by the nucleophilic nitrogen on

cause changes in the finally shape of the enzyme’s active site.However, if you have a lower pH than the the pKa value of the amine group there will be changes as they become protonated and the NH2 change to NH3+ therefore, they do not stay same.But if you have pH , which is high than the pka value of the amine group of the amino acid then there will be no changes on the amine group (NH2) so, it stay