1. Aims a) To find the molar absorptivity of salicylic acid by plotting a graph of absorbance against the concentration of salicylic acid, using the standard solution. b) To find the concentration of aspirin at the various time intervals using the molar absorptivity value in the previous part, initial concentration of aspirin and the concentration of salicylic acid obtained from the decomposition of the aspirin pill. c) Lastly, to calculate the rate constant of the decomposition of aspirin by plotting
2-hydroxybenzoic acid, C6H4(OH)COOH - commercially known as salicylic acid exists as a colourless, crystalline organic carboxylic acid. It is partially soluble in water and completely soluble in ethanol and ether. This acid is very commonly used in the preparation of its ester derivatives as it contains both a hydroxyl (-OH) and a carboxylic (-COOH) group. Due to the presence of these functional groups, it is able to react with both an acid and an alcohol.1 (“Salicylic acid”). The very first preparation
Proactiv the difference is the ingredient it is made with benzoyl peroxide. “This agent kills bacteria that leads to breakouts. By killing bacteria, benzoyl peroxide unclogs pores leading to clearer skin. Neutrogena’s main ingredient is salicylic acid. This acid reduces the oiliness of skin, and thus clogged pores, the major causes of breakouts.” (Sundt) This difference between the two products is enough to know which product is ultimately the leading treatment. Another beauty aid that is used to
Preparing the stock solution-The stock solution of Salicylic acid needed to be prepared well in advance before the experiment began. To do so, 1.73g of Salicylic Acid was weighed using the weighing balance. After Salicylic acid was weighed, it was transferred to a standard flask of 100cm3 and, 100cm3 of pure Ethanol (C2H5OH), was poured into the standard flask that contained the Salicylic acid. Shaking the flask gently for C2H5OH and Salicylic acid to dissolve and then keeping it covered so that
plants, and are considered a process of evolution as they have evolved in order to adapt to the change in the environment. In this investigation we will be observing the results of both types of plants under harsh conditions. It is preferable that the Polyploidy plant will survive harsher conditions as they have actually developed due to the change in their biosphere therefore making it more likely that they will survive unfavourable conditions. In this experiment we will be taking a look at which
Purpose: The main goal of this lab experiment is to synthesize acetylsalicylic acid through using different processes such as crystallization and filtration. Additionally, determining the purity of the synthesize product alongside with a commercial ASA provided in the lab, through using one of the melting point apparatus or conducting a USP test are also the objectives of this experiment. Results Discussion: As discussed in the lab manual, there are certain instructions which apply to proper
1) Percentage yield experiment: First we measured 20cm3 of sulphuric acid into a beaker using a measuring cylinder, this will help us determine the percentage yield at the end of the experiment. We then heated the beaker containing the sulphuric acid using a Bunsen burner in order to heat it up for the copper oxide to mix with. We then weighed out 1.02g of copper oxide and added it to the acid and stirred it whilst doing so, we did that until the liquid turned blue, this proves that the chemicals
affordability and effectiveness, acetylsalicylic acid, or Aspirin, is a widely popular over-the-counter medication2. Part of a medication class called ‘NSAID’s (non-steroid anti-inflammatory drugs), aspirin is commonly used in the treatment of simple inflammatory ailments such as headaches and low-grade fevers2. The synthesis of aspirin is relatively simple. The two reactants are acetic anhydride and salicylic acid and the products are acetylsalicylic acid and acetic acid1. One method used to analyze
In this experiment, aspirin was synthesized from acetic anhydride and salicylic acid made in order to characterize its properties and determine its purity. The purity of the aspirin was examined by its melting point, thin layer chromatography, and UV spectroscopy. Introduction: Aspirin and acetic acid is synthesized by the formation of acetic anhydride and salicylic acid (Salicylic Acid + Acetic Anhydride Acetyl Salicylic Acid + Acetic Acid1). During the synthesis, the catalyst donates an H+ that
On a molecular basis the identification of the aspirin, acetaminophen, and caffeine via Rf values can be understood when looking at molecular symmetry and different functional groups. Caffeine had the lowest Rf value, with the caffeine crystals yielding a Rf value of 0.21. This is due to caffeine being the most polar molecules out of the three components. Caffeine has 4 Nitrogen atoms in the compound that are not symmetrically balanced out, along with two amide groups that are also not symmetric
Most of you must have an experience in feeling sweating, feeling burn, and skin turning to red, as red as skin of shrimp when it was being boiling when being exposed to direct sunlight. All of you must feel not comfortable with those conditions, right? So, today I am going to talk about the sunburn problem and the solution to this problem. I want to tell you about this as I am obsessed with health, skin care and skin beauty and I have gained much information from many sources that I have read. So
Citric acid, aspirin and sodium hydrogen carbonate are the main constituents of alka seltzer. Its main role is to reduce headaches, period pains, migraines, muscular pains and symptoms of colds and flues, as well has curing problems related with an upset stomach. Aspirin works to reduce pain and swellings; it is an anti- inflammatory drug and belongs to a group of drugs called NSAIDs as it does not contain steroids. The enzyme cyclo-oxygenase which speeds up the production of prostaglandins is blocked
lip balm formula helps remove cracked and peeling skin, and allow soothing and healing dry lip, and the menthol and camphor ingredients provide cool and refreshing tingle. The natural lip balm formula based on four main raw materials, which are Salicylic Acid, Phenol, Menthol and Camphor. Regarding to those four material, they are considered as hazardous materials, which are Eco-toxicity to human and to our environment. For the acquisition of those four raw materials, the
to be between 126-129 ˚C. This temperature range of initial to final melting point has a small and sharp temperature range of only 3˚C, which is within the acceptable limits of the 128-137˚C1 literature value for Aspirin (Acetylsalicylic Acid/2-acetoxybenzoic acid), if located slightly toward the beginning of the literature melting temperature range. Therefore, the narrow melting point range, which falls within the standard literature value range results, indicate the reliability purity of the sample
Results and Discussion One of the objectives of this exercise is to synthesize acetylsalicylic acid (aspirin) from salicylic acid. The mechanism for this synthesis is through nucleophilic acyl substitution. Acetic anhydride was the acetylation reagent used with the salicylic acid. The mechanisms and the reaction involved in the synthesis are seen in the following figure. 1.00 gram of fine white salicylic acid powder was weighed in a clean, dry 125mL Erlenmeyer flask. 3mL of strong smelling, clear colorless
(acetylsalicylic acid) is an aromatic compound that contains an ester- functional group and a carboxylic acid- functional group. Aspirin is commonly used as a pain reliever (analgesic), an anti-inflammatory, an anti-coagulant (prevent platelet aggregation) and an antipyretic (to reduce fever) pill. It helps to prevent strokes, heart attacks and blood clot formation. It can be produced from salicylic acid and acetic anhydride, with acetic acid as its by-product. However, salicylic acid consists of the
Initially a 1:1:1 mixture of an unknown acid, base, and neutral compound was obtained with the goal of being separated through extraction and then further purified through recrystallization. Since the mixture was a 1:1:1 ratio, this means the amount present was .333 grams for each compound as this is important for calculating the percent recovery from extraction. The percent recovery is the percentage of the original product that is recovered, in this case the percent of the initial 0.33g that is
Using the equation of the titration in the experiment (Equation 1), calculate the number of moles of the ascorbic acid reacting. 4. Then proceed to calculating the concentration in mol. dm3 of the ascorbic acid in the solutions that was obtained. Data Collection and Processing Raw Data Table 1: Amount of Iodine Reacting (± 0.05cm3) in the titration FT 1 FT 2 FT 3 FT 4 FT 5 Trial 1 1.9 1.8 1.8 1.5 1.6 Trial 2
In this experiment, extraction was used as a separation technique to separate the acid, base, and neutral compounds. In extraction, two immiscible solvents with opposite polarities are used to dissolve different parts of the solute with different polarities, so they form two distinct liquid layers. In this experiment, methanol, an organic solvent, and an aqueous solution were used as the two immiscible solvents. The extraction solvent must also be capable of dissolving one of the mixture components
dissociation of the acid: HA ⇄ H+ + A- Hence, when acid is added, the excess H+ reacts with the A- to form more HA, lowering the pH and minimising the effect of the addition of acid. When alkali is added, the OH- reacts with the dissociated H+ to form water, which reduces the effect of the alkali by restoring the pH to normal levels. Alka Seltzer acts as a buffer because the citrate ions in solution (C6H5O73-) are able to react with H+ when acid is added, to form citric acid, C6H8O7. This neutralises