Biomaterials have played an indispensable role in biomedical applications for centuries. Early designs of these materials primarily focus on matching the mechanical and physiological function of the replaced part without inducing any adverse reaction within the system [1]. With the advancements in the biological and engineering sciences, biomaterials are being utilized in applications which are intended to engineer tissues, intelligent materials, tissue culture, drug delivery systems, artificial organs, and biomimetic systems and materials [1-2]. Biomaterials can be made using natural materials, metals, polymers, ceramics, and composites. Among these materials, the composite biomaterials show the most progressive innovations for biomedical applications as these comprise of at least 2 different kinds of materials, which can either be used as a matrix or filler, with their intrinsic properties remain distinct even after putting them together. In addition, a composite is made of materials which complement the properties of the other by, for example, filling the weakness of the matrix with a selected material for fillers [2]. The skin and mucosal barrier has a natural tendency to produce an antimicrobial barrier to make the inner environment of the body sterile. The microorganisms which threaten the system are enclosed inside this barrier and are not allowed to go out [3]. But, the presence of an injury causes weakening in the antimicrobial barrier, provided by the skin, against