Pytochemistry Research Paper

Phytochemistry

Phytochemical studies of Cissus quadrangularis have shown the presence of various versatile constituents such as flavanoids, triterpenoids, Vitamin C, stilbene derivatives and many others, e.g. resveratrol, piceatannol, pallidol perthenocissin and phytosterols. Out of which ascorbic acid, triterpene, β-sitosterol, ketosteroid, two asymmetrical tetracyclic triterpenoids and calcium were identified as major constituents of this plant. Cissus quadrangularis have high contents of anabolic steroidal substances, ascorbic acid, carotene, and calcium.8,9,10 The plant contains ascorbic acid 479 mg and carotene 267 mg per 100 g freshly prepared paste in addition to calcium oxalate. The stem of the plant contains two asymmetric tetracyclic

As per the studies Cissus quadrangularis acts by increasing metabolism and uptake of minerals like calcium, sulpher and strontium by osteoblasts in remodeling of fracture bone. Vitamin and steroids present in Cissus quadrangularis is considered to have potent fracture healing properties. There are believes that vitamin C is one of the constituent of Cissus quadrangularis which gives the potent fracture healing properties,but is not so because the administration of vitamin C to the normal animal did not produce such a beneficial effect,this may be due to some phytogenic steroid isolated from Cissus quadrangularis which is believe to be the main constituent in Cissus

in body pains decoction of the shoots with dry ginger and black pepper is given. The plant is anthelmintic in nature. And it also exhibit cardiotonic property. in dyspepsia and in indigestion Young shoots are used.

Side Effects of Cissus quadrangularis: It is safe for short-term use, but long-term effects have not been well documented. Some side effects include Gastrointestinal Problems like flatulence, diarrhea, dry mouth and patients may experience Headache and insomnia, Cissus quadrangularis contains hydroxycitric acid (HCA), which may suppress appetite and in lab studies it is found that it inhibits the enzyme ATP citrate lipase, This may block conversion of carbohydrates into fat which Decreased appetite and lead to weight loss. Drug Interactions: Cissus quadrangularis have a property to lower blood glucose level so it may interact with diabetes drugs. So while prescribing any hypoglycemic agent from Ayurveda or from modern medicine we need to take care for drug interaction to avoid