Excedrin Synthesis Lab Report

Therefore, liquid-liquid and acid-base extraction techniques were successfully performed to separate the components of the Excedrin tablet. According to the TLC analysis results, the compounds (aspirin, acetaminophen, and caffeine) were successfully isolated from the analgesic (Excedrin tablet). In figure 1, the separation of the compound in the TLC analysis correlates with the TLC analysis in figure 2. Furthermore, Rf index calculations of the TLC analysis demonstrated that the compounds (aspirin, acetaminophen, and caffeine) were separated. The Rf calculations of aspirin in table 1 shows an Rf value of .491; however, in table 2 the Rf value of aspirin was calculated to be .784. This Rf value is the higher among the other compounds because the Rf values decreases from aspirin to caffeine; therefore, this suggests that the

Thus, a higher percent yield was calculated for acetaminophen. Although, a second filtration was performed; however, a very low concentration of acetaminophen was recovered as a result of human errors, and the transfer of solution/solid contributed to product loss. However, the mass use to calculate percent yield was the first mass recorded because it may be more consistent than the mass measured after the second filtration. However, for further experiments, the percent yield must be calculated with the corresponding mass of product (actual yield) even though there is loss of product, the actual yield is the final concentration of the recovered product in the experiment. Thus, the results may be more conclusive if the actual percent yield was used. However, in this particular experiment, despite this deviation, aspirin, caffeine and acetaminophen compounds were successfully isolated from the analgesic